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8s4g
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8s4g is ON HOLD Authors: Hoefler, A., Yu, J., Chang, L., Zhang, Z., Yang, J., Boland, A., Barford, D. Description: Cryo-EM structure of the Anaphas...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of the Anaphase-promoting complex/cyclosome (APC/C) bound to co-activator Cdh1 at 3.2 Angstrom resolution== | |
| - | + | <StructureSection load='8s4g' size='340' side='right'caption='[[8s4g]], [[Resolution|resolution]] 3.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8s4g]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8S4G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8S4G FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8s4g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8s4g OCA], [https://pdbe.org/8s4g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8s4g RCSB], [https://www.ebi.ac.uk/pdbsum/8s4g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8s4g ProSAT]</span></td></tr> |
| - | [[Category: Barford | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/APC10_HUMAN APC10_HUMAN] Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.<ref>PMID:18485873</ref> |
| - | [[Category: Hoefler | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: Yu | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Barford D]] | ||
| + | [[Category: Boland A]] | ||
| + | [[Category: Chang L]] | ||
| + | [[Category: Hoefler A]] | ||
| + | [[Category: Yang J]] | ||
| + | [[Category: Yu J]] | ||
| + | [[Category: Zhang Z]] | ||
Current revision
Cryo-EM structure of the Anaphase-promoting complex/cyclosome (APC/C) bound to co-activator Cdh1 at 3.2 Angstrom resolution
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Categories: Homo sapiens | Large Structures | Barford D | Boland A | Chang L | Hoefler A | Yang J | Yu J | Zhang Z
