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1do8

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[[Image:1do8.png|left|200px]]
 
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{{STRUCTURE_1do8| PDB=1do8 | SCENE= }}
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==CRYSTAL STRUCTURE OF A CLOSED FORM OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME==
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<StructureSection load='1do8' size='340' side='right'caption='[[1do8]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF A CLOSED FORM OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1do8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DO8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DO8 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10700286}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=OXL:OXALATE+ION'>OXL</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1do8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1do8 OCA], [https://pdbe.org/1do8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1do8 RCSB], [https://www.ebi.ac.uk/pdbsum/1do8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1do8 ProSAT]</span></td></tr>
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[[1do8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DO8 OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/MAOM_HUMAN MAOM_HUMAN]
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<ref group="xtra">PMID:010700286</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/do/1do8_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1do8 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Floyd, D L.]]
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[[Category: Large Structures]]
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[[Category: Loeber, G.]]
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[[Category: Floyd DL]]
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[[Category: Tong, L.]]
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[[Category: Loeber G]]
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[[Category: Yang, Z.]]
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[[Category: Tong L]]
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[[Category: And one mostly extended]]
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[[Category: Yang Z]]
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[[Category: Four domains: one with rossmann fold]]
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[[Category: One mostly helical]]
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[[Category: One with parallel alpha-beta fold]]
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[[Category: Oxidative decarboxylase]]
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[[Category: Oxidoreductase]]
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Current revision

CRYSTAL STRUCTURE OF A CLOSED FORM OF HUMAN MITOCHONDRIAL NAD(P)+-DEPENDENT MALIC ENZYME

PDB ID 1do8

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