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1jth

From Proteopedia

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{{Seed}}
 
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[[Image:1jth.png|left|200px]]
 
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==Crystal structure and biophysical properties of a complex between the N-terminal region of SNAP25 and the SNARE region of syntaxin 1a==
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The line below this paragraph, containing "STRUCTURE_1jth", creates the "Structure Box" on the page.
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<StructureSection load='1jth' size='340' side='right'caption='[[1jth]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1jth]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JTH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JTH FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jth FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jth OCA], [https://pdbe.org/1jth PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jth RCSB], [https://www.ebi.ac.uk/pdbsum/1jth PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jth ProSAT]</span></td></tr>
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{{STRUCTURE_1jth| PDB=1jth | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SNP25_RAT SNP25_RAT] t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jt/1jth_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jth ConSurf].
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<div style="clear:both"></div>
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===Crystal structure and biophysical properties of a complex between the N-terminal region of SNAP25 and the SNARE region of syntaxin 1a===
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==See Also==
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*[[Synaptosomal-associated protein|Synaptosomal-associated protein]]
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*[[Syntaxin 3D structures|Syntaxin 3D structures]]
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<!--
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__TOC__
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The line below this paragraph, {{ABSTRACT_PUBMED_11533035}}, adds the Publication Abstract to the page
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 11533035 is the PubMed ID number.
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[[Category: Large Structures]]
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-->
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{{ABSTRACT_PUBMED_11533035}}
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==About this Structure==
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1JTH is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JTH OCA].
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==Reference==
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Crystal structure and biophysical properties of a complex between the N-terminal SNARE region of SNAP25 and syntaxin 1a., Misura KM, Gonzalez LC Jr, May AP, Scheller RH, Weis WI, J Biol Chem. 2001 Nov 2;276(44):41301-9. Epub 2001 Aug 30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11533035 11533035]
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[[Category: Protein complex]]
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[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Jr., L C.Gonzalez.]]
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[[Category: Gonzalez Jr LC]]
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[[Category: May, A P.]]
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[[Category: May AP]]
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[[Category: Misura, K M.S.]]
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[[Category: Misura KMS]]
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[[Category: Scheller, R H.]]
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[[Category: Scheller RH]]
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[[Category: Weis, W I.]]
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[[Category: Weis WI]]
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[[Category: Coiled-coil]]
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[[Category: Polar layer]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 20:46:34 2008''
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Current revision

Crystal structure and biophysical properties of a complex between the N-terminal region of SNAP25 and the SNARE region of syntaxin 1a

PDB ID 1jth

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