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1kol

From Proteopedia

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{{Seed}}
 
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[[Image:1kol.png|left|200px]]
 
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<!--
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==Crystal structure of formaldehyde dehydrogenase==
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The line below this paragraph, containing "STRUCTURE_1kol", creates the "Structure Box" on the page.
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<StructureSection load='1kol' size='340' side='right'caption='[[1kol]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1kol]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KOL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KOL FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_1kol| PDB=1kol | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kol FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kol OCA], [https://pdbe.org/1kol PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kol RCSB], [https://www.ebi.ac.uk/pdbsum/1kol PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kol ProSAT]</span></td></tr>
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</table>
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===Crystal structure of formaldehyde dehydrogenase===
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== Function ==
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[https://www.uniprot.org/uniprot/FADH_PSEPU FADH_PSEPU] Catalyzes the NAD(+)-dependent oxidation of formaldehyde and acetoaldehyde as well as long-chain alcohols but is inactive against propionaldehyde, butyraldehyde, methanol and ethanol. Can also catalyze the dismutation of a wide range of aldehydes such as formaldehyde.<ref>PMID:6526822</ref> <ref>PMID:9059646</ref>
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== Evolutionary Conservation ==
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<!--
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_12445786}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 12445786 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ko/1kol_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_12445786}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1KOL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_putida Pseudomonas putida]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KOL OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kol ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Crystal structure of formaldehyde dehydrogenase from Pseudomonas putida: the structural origin of the tightly bound cofactor in nicotinoprotein dehydrogenases., Tanaka N, Kusakabe Y, Ito K, Yoshimoto T, Nakamura KT, J Mol Biol. 2002 Nov 29;324(3):519-33. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12445786 12445786]
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<references/>
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[[Category: Formaldehyde dehydrogenase]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Pseudomonas putida]]
[[Category: Pseudomonas putida]]
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[[Category: Single protein]]
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[[Category: Ito K]]
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[[Category: Ito, K.]]
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[[Category: Kusakabe Y]]
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[[Category: Kusakabe, Y.]]
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[[Category: Nakamura KT]]
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[[Category: Nakamura, K T.]]
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[[Category: Tanaka N]]
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[[Category: Tanaka, N.]]
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[[Category: Yoshimoto T]]
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[[Category: Yoshimoto, T.]]
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[[Category: Dehydrogenase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 10:39:48 2008''
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Current revision

Crystal structure of formaldehyde dehydrogenase

PDB ID 1kol

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