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1n1j

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{{Seed}}
 
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[[Image:1n1j.png|left|200px]]
 
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==Crystal structure of the NF-YB/NF-YC histone pair==
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The line below this paragraph, containing "STRUCTURE_1n1j", creates the "Structure Box" on the page.
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<StructureSection load='1n1j' size='340' side='right'caption='[[1n1j]], [[Resolution|resolution]] 1.67&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1n1j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N1J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N1J FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.67&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n1j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n1j OCA], [https://pdbe.org/1n1j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n1j RCSB], [https://www.ebi.ac.uk/pdbsum/1n1j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n1j ProSAT]</span></td></tr>
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{{STRUCTURE_1n1j| PDB=1n1j | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NFYB_HUMAN NFYB_HUMAN] Stimulates the transcription of various genes by recognizing and binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin and beta-actin genes.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n1/1n1j_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1n1j ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of the NF-YB/NF-YC histone pair===
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==See Also==
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*[[Nuclear transcription factor Y|Nuclear transcription factor Y]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12401788}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 12401788 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12401788}}
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==About this Structure==
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1N1J is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N1J OCA].
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==Reference==
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The NF-YB/NF-YC structure gives insight into DNA binding and transcription regulation by CCAAT factor NF-Y., Romier C, Cocchiarella F, Mantovani R, Moras D, J Biol Chem. 2003 Jan 10;278(2):1336-45. Epub 2002 Oct 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12401788 12401788]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Protein complex]]
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[[Category: Large Structures]]
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[[Category: Cocchiarella, F.]]
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[[Category: Cocchiarella F]]
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[[Category: Mantovani, R.]]
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[[Category: Mantovani R]]
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[[Category: Moras, D.]]
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[[Category: Moras D]]
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[[Category: Romier, C.]]
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[[Category: Romier C]]
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[[Category: Histone-like pair]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 07:53:24 2008''
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Current revision

Crystal structure of the NF-YB/NF-YC histone pair

PDB ID 1n1j

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