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1n7f

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[[Image:1n7f.png|left|200px]]
 
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{{STRUCTURE_1n7f| PDB=1n7f | SCENE= }}
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==Crystal structure of the sixth PDZ domain of GRIP1 in complex with liprin C-terminal peptide==
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<StructureSection load='1n7f' size='340' side='right'caption='[[1n7f]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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===Crystal structure of the sixth PDZ domain of GRIP1 in complex with liprin C-terminal peptide===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1n7f]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N7F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1N7F FirstGlance]. <br>
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{{ABSTRACT_PUBMED_12493751}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1n7f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1n7f OCA], [https://pdbe.org/1n7f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1n7f RCSB], [https://www.ebi.ac.uk/pdbsum/1n7f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1n7f ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1n7f]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1N7F OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/LIPA1_HUMAN LIPA1_HUMAN] May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates.<ref>PMID:7796809</ref>
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==Reference==
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== Evolutionary Conservation ==
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<ref group="xtra">PMID:012493751</ref><references group="xtra"/>
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n7/1n7f_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1n7f ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Eom, S H.]]
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[[Category: Eom SH]]
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[[Category: Im, Y J.]]
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[[Category: Im YJ]]
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[[Category: Kang, G B.]]
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[[Category: Kang GB]]
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[[Category: Kim, E.]]
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[[Category: Kim E]]
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[[Category: Lee, J H.]]
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[[Category: Lee JH]]
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[[Category: Park, S H.]]
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[[Category: Park SH]]
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[[Category: Rho, S H.]]
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[[Category: Rho SH]]
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[[Category: Sheng, M.]]
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[[Category: Sheng M]]
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[[Category: Grip]]
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[[Category: Liprin]]
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[[Category: Pdz]]
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[[Category: Protein binding]]
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Current revision

Crystal structure of the sixth PDZ domain of GRIP1 in complex with liprin C-terminal peptide

PDB ID 1n7f

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