1nww
From Proteopedia
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| - | [[Image:1nww.png|left|200px]] | ||
| - | + | ==Limonene-1,2-epoxide hydrolase== | |
| + | <StructureSection load='1nww' size='340' side='right'caption='[[1nww]], [[Resolution|resolution]] 1.20Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1nww]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rhodococcus_erythropolis Rhodococcus erythropolis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NWW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NWW FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HPN:HEPTANAMIDE'>HPN</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nww FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nww OCA], [https://pdbe.org/1nww PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nww RCSB], [https://www.ebi.ac.uk/pdbsum/1nww PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nww ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/LIMA_RHOER LIMA_RHOER] Catalyzes the conversion of limonene-1,2-epoxide to limonene-1,2-diol. Can use both the (-) and (+) isomers of limonene-1,2-epoxide as substrates and also has some activity with 1-methylcyclohexene oxide, cyclohexene oxide and indene oxide as substrates. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nw/1nww_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nww ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Epoxide hydrolase 3D structures|Epoxide hydrolase 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
| - | [[ | + | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | [[Category: | + | |
[[Category: Rhodococcus erythropolis]] | [[Category: Rhodococcus erythropolis]] | ||
| - | [[Category: Arand | + | [[Category: Arand M]] |
| - | [[Category: Bergfors | + | [[Category: Bergfors T]] |
| - | + | [[Category: Hallberg BM]] | |
| - | [[Category: Hallberg | + | [[Category: Jones TA]] |
| - | [[Category: Jones | + | [[Category: Mowbray SL]] |
| - | [[Category: Mowbray | + | [[Category: Oesch F]] |
| - | [[Category: Oesch | + | [[Category: Zou J]] |
| - | + | [[Category: De Bont JAM]] | |
| - | [[Category: Zou | + | [[Category: Van der Werf MJ]] |
| - | [[Category: | + | |
| - | [[Category: | + | |
Current revision
Limonene-1,2-epoxide hydrolase
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