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1wkq

From Proteopedia

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{{Seed}}
 
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[[Image:1wkq.png|left|200px]]
 
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==Crystal Structure of Bacillus subtilis Guanine Deaminase. The first domain-swapped structure in the cytidine deaminase superfamily==
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The line below this paragraph, containing "STRUCTURE_1wkq", creates the "Structure Box" on the page.
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<StructureSection load='1wkq' size='340' side='right'caption='[[1wkq]], [[Resolution|resolution]] 1.17&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1wkq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WKQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WKQ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.17&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_1wkq| PDB=1wkq | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wkq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wkq OCA], [https://pdbe.org/1wkq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wkq RCSB], [https://www.ebi.ac.uk/pdbsum/1wkq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wkq ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GUAD_BACSU GUAD_BACSU] Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wk/1wkq_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wkq ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure of Bacillus subtilis Guanine Deaminase. The first domain-swapped structure in the cytidine deaminase superfamily===
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==See Also==
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*[[Deaminase 3D structures|Deaminase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_15180998}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 15180998 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15180998}}
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==About this Structure==
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1WKQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WKQ OCA].
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==Reference==
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Crystal structure of Bacillus subtilis guanine deaminase: the first domain-swapped structure in the cytidine deaminase superfamily., Liaw SH, Chang YJ, Lai CT, Chang HC, Chang GG, J Biol Chem. 2004 Aug 20;279(34):35479-85. Epub 2004 Jun 4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15180998 15180998]
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Crystallization and preliminary crystallographic analysis of Bacillus subtilis guanine deaminase., Chang YJ, Huang CH, Hu CY, Liaw SH, Acta Crystallogr D Biol Crystallogr. 2004 Jun;60(Pt 6):1152-4. Epub 2004, May 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15159585 15159585]
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[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Guanine deaminase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Chang YJ]]
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[[Category: Chang, Y J.]]
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[[Category: Lai CT]]
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[[Category: Lai, C T.]]
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[[Category: Liaw SH]]
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[[Category: Liaw, S H.]]
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[[Category: Domain swap]]
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[[Category: Guanine deaminase]]
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[[Category: Structural plasticity]]
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[[Category: Substrate specificity]]
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[[Category: The cytidine deaminase superfamily]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 16:37:33 2008''
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Current revision

Crystal Structure of Bacillus subtilis Guanine Deaminase. The first domain-swapped structure in the cytidine deaminase superfamily

PDB ID 1wkq

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