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1wm1

From Proteopedia

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{{Seed}}
 
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[[Image:1wm1.png|left|200px]]
 
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==Crystal Structure of Prolyl Aminopeptidase, Complex with Pro-TBODA==
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The line below this paragraph, containing "STRUCTURE_1wm1", creates the "Structure Box" on the page.
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<StructureSection load='1wm1' size='340' side='right'caption='[[1wm1]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1wm1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Serratia_marcescens Serratia marcescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WM1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WM1 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PTB:(5-TERT-BUTYL-1,3,4-OXADIAZOL-2-YL)[(2R)-PYRROLIDIN-2-YL]METHANONE'>PTB</scene></td></tr>
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{{STRUCTURE_1wm1| PDB=1wm1 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wm1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wm1 OCA], [https://pdbe.org/1wm1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wm1 RCSB], [https://www.ebi.ac.uk/pdbsum/1wm1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wm1 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PIP_SERMA PIP_SERMA] Specifically catalyzes the removal of N-terminal proline residues from peptides.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wm/1wm1_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wm1 ConSurf].
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<div style="clear:both"></div>
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===Crystal Structure of Prolyl Aminopeptidase, Complex with Pro-TBODA===
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==See Also==
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*[[Aminopeptidase 3D structures|Aminopeptidase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_12893291}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 12893291 is the PubMed ID number.
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{{ABSTRACT_PUBMED_12893291}}
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==About this Structure==
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1WM1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Serratia_marcescens Serratia marcescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WM1 OCA].
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==Reference==
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Novel inhibitor for prolyl aminopeptidase from Serratia marcescens and studies on the mechanism of substrate recognition of the enzyme using the inhibitor., Inoue T, Ito K, Tozaka T, Hatakeyama S, Tanaka N, Nakamura KT, Yoshimoto T, Arch Biochem Biophys. 2003 Aug 15;416(2):147-54. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12893291 12893291]
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[[Category: Prolyl aminopeptidase]]
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[[Category: Serratia marcescens]]
[[Category: Serratia marcescens]]
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[[Category: Single protein]]
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[[Category: Hatakeyama S]]
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[[Category: Hatakeyama, S.]]
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[[Category: Inoue T]]
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[[Category: Inoue, T.]]
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[[Category: Ito K]]
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[[Category: Ito, K.]]
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[[Category: Nakajima Y]]
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[[Category: Nakajima, Y.]]
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[[Category: Nakamura KT]]
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[[Category: Nakamura, K T.]]
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[[Category: Tanaka N]]
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[[Category: Tanaka, N.]]
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[[Category: Tozaka T]]
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[[Category: Tozaka, T.]]
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[[Category: Yoshimoto T]]
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[[Category: Yoshimoto, T.]]
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[[Category: Complex with inhibitor]]
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[[Category: Proline iminopeptidase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 14:22:38 2008''
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Current revision

Crystal Structure of Prolyl Aminopeptidase, Complex with Pro-TBODA

PDB ID 1wm1

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