This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1wm9

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:32, 13 March 2024) (edit) (undo)
 
(11 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1wm9.png|left|200px]]
 
-
<!--
+
==Structure of GTP cyclohydrolase I from Thermus thermophilus HB8==
-
The line below this paragraph, containing "STRUCTURE_1wm9", creates the "Structure Box" on the page.
+
<StructureSection load='1wm9' size='340' side='right'caption='[[1wm9]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1wm9]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WM9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WM9 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
{{STRUCTURE_1wm9| PDB=1wm9 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wm9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wm9 OCA], [https://pdbe.org/1wm9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wm9 RCSB], [https://www.ebi.ac.uk/pdbsum/1wm9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wm9 ProSAT], [https://www.topsan.org/Proteins/RSGI/1wm9 TOPSAN]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/Q5SH52_THET8 Q5SH52_THET8]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wm/1wm9_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wm9 ConSurf].
 +
<div style="clear:both"></div>
-
===Structure of GTP cyclohydrolase I from Thermus thermophilus HB8===
+
==See Also==
-
 
+
*[[Cyclohydrolase 3D structures|Cyclohydrolase 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_16169877}}, adds the Publication Abstract to the page
+
[[Category: Large Structures]]
-
(as it appears on PubMed at http://www.pubmed.gov), where 16169877 is the PubMed ID number.
+
[[Category: Thermus thermophilus HB8]]
-
-->
+
[[Category: Tanaka Y]]
-
{{ABSTRACT_PUBMED_16169877}}
+
-
 
+
-
==About this Structure==
+
-
1WM9 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WM9 OCA].
+
-
 
+
-
==Reference==
+
-
Novel reaction mechanism of GTP cyclohydrolase I. High-resolution X-ray crystallography of Thermus thermophilus HB8 enzyme complexed with a transition state analogue, the 8-oxoguanine derivative., Tanaka Y, Nakagawa N, Kuramitsu S, Yokoyama S, Masui R, J Biochem. 2005 Sep;138(3):263-75. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16169877 16169877]
+
-
[[Category: GTP cyclohydrolase I]]
+
-
[[Category: Single protein]]
+
-
[[Category: Thermus thermophilus]]
+
-
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+
-
[[Category: Tanaka, Y.]]
+
-
[[Category: Beta barrel]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Pteridine]]
+
-
[[Category: Riken structural genomics/proteomics initiative]]
+
-
[[Category: Rsgi]]
+
-
[[Category: Structural genomic]]
+
-
[[Category: Tetrahydrobiopterin]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 13:50:15 2008''
+

Current revision

Structure of GTP cyclohydrolase I from Thermus thermophilus HB8

PDB ID 1wm9

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1wm9"
Personal tools