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1wra

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{{Seed}}
 
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[[Image:1wra.png|left|200px]]
 
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<!--
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==Crystal Structure of Phosphorylcholine Esterase Domain of the Virulence Factor Choline Binding Protein E from Streptococcus Pneumoniae==
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The line below this paragraph, containing "STRUCTURE_1wra", creates the "Structure Box" on the page.
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<StructureSection load='1wra' size='340' side='right'caption='[[1wra]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1wra]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_R6 Streptococcus pneumoniae R6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WRA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WRA FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=PC:PHOSPHOCHOLINE'>PC</scene></td></tr>
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{{STRUCTURE_1wra| PDB=1wra | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wra FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wra OCA], [https://pdbe.org/1wra PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wra RCSB], [https://www.ebi.ac.uk/pdbsum/1wra PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wra ProSAT]</span></td></tr>
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</table>
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===Crystal Structure of Phosphorylcholine Esterase Domain of the Virulence Factor Choline Binding Protein E from Streptococcus Pneumoniae===
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== Function ==
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[https://www.uniprot.org/uniprot/Q8DQ62_STRR6 Q8DQ62_STRR6]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_15908436}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 15908436 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wr/1wra_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_15908436}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1WRA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WRA OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wra ConSurf].
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<div style="clear:both"></div>
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==Reference==
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__TOC__
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Crystal structure of phosphorylcholine esterase domain of the virulence factor choline-binding protein e from streptococcus pneumoniae: new structural features among the metallo-beta-lactamase superfamily., Garau G, Lemaire D, Vernet T, Dideberg O, Di Guilmi AM, J Biol Chem. 2005 Aug 5;280(31):28591-600. Epub 2005 May 20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15908436 15908436]
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</StructureSection>
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[[Category: Large Structures]]
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Identification of the teichoic acid phosphorylcholine esterase in Streptococcus pneumoniae., Vollmer W, Tomasz A, Mol Microbiol. 2001 Mar;39(6):1610-22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11260477 11260477]
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[[Category: Streptococcus pneumoniae R6]]
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[[Category: Dideberg O]]
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A novel solenoid fold in the cell wall anchoring domain of the pneumococcal virulence factor LytA., Fernandez-Tornero C, Lopez R, Garcia E, Gimenez-Gallego G, Romero A, Nat Struct Biol. 2001 Dec;8(12):1020-4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11694890 11694890]
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[[Category: Garau G]]
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[[Category: Glycerophosphocholine cholinephosphodiesterase]]
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[[Category: Single protein]]
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[[Category: Streptococcus pneumoniae]]
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[[Category: Dideberg, O.]]
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[[Category: Garau, G.]]
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[[Category: Binding]]
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[[Category: Cbpe]]
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[[Category: Choline]]
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[[Category: Domain]]
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[[Category: Esterase]]
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[[Category: Iron]]
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[[Category: Lactamase]]
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[[Category: Metallo]]
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[[Category: Pce]]
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[[Category: Phosphocholine]]
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[[Category: Pneum]]
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[[Category: Streptococcus]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 06:04:53 2008''
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Current revision

Crystal Structure of Phosphorylcholine Esterase Domain of the Virulence Factor Choline Binding Protein E from Streptococcus Pneumoniae

PDB ID 1wra

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