1wu3

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{{Seed}}
 
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[[Image:1wu3.png|left|200px]]
 
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==Crystal structure of recombinant murine interferon beta==
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The line below this paragraph, containing "STRUCTURE_1wu3", creates the "Structure Box" on the page.
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<StructureSection load='1wu3' size='340' side='right'caption='[[1wu3]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1wu3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1rmi 1rmi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WU3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WU3 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wu3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wu3 OCA], [https://pdbe.org/1wu3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wu3 RCSB], [https://www.ebi.ac.uk/pdbsum/1wu3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wu3 ProSAT]</span></td></tr>
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{{STRUCTURE_1wu3| PDB=1wu3 | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/IFNB_MOUSE IFNB_MOUSE] Has antiviral, antibacterial and anticancer activities.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wu/1wu3_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wu3 ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of recombinant murine interferon beta===
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==See Also==
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*[[Interferon 3D structures|Interferon 3D structures]]
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*[[Multiple sclerosis|Multiple sclerosis]]
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__TOC__
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The line below this paragraph, {{ABSTRACT_PUBMED_7473712}}, adds the Publication Abstract to the page
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 7473712 is the PubMed ID number.
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[[Category: Large Structures]]
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{{ABSTRACT_PUBMED_7473712}}
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==About this Structure==
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1WU3 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1rmi 1rmi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WU3 OCA].
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==Reference==
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Refined crystal structure of recombinant murine interferon-beta at 2.15 A resolution., Senda T, Saitoh S, Mitsui Y, J Mol Biol. 1995 Oct 13;253(1):187-207. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7473712 7473712]
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Three-dimensional crystal structure of recombinant murine interferon-beta., Senda T, Shimazu T, Matsuda S, Kawano G, Shimizu H, Nakamura KT, Mitsui Y, EMBO J. 1992 Sep;11(9):3193-201. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1505514 1505514]
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Structural, functional and evolutionary implications of the three-dimensional crystal structure of murine interferon-beta., Mitsui Y, Senda T, Shimazu T, Matsuda S, Utsumi J, Pharmacol Ther. 1993;58(1):93-132. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8415875 8415875]
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[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Single protein]]
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[[Category: Mitsui Y]]
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[[Category: Mitsui, Y.]]
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[[Category: Saitoh S]]
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[[Category: Saitoh, S.]]
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[[Category: Senda T]]
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[[Category: Senda, T.]]
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[[Category: Alpha-helix-bundle]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 00:23:53 2008''
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Current revision

Crystal structure of recombinant murine interferon beta

PDB ID 1wu3

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