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1wur

From Proteopedia

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[[Image:1wur.png|left|200px]]
 
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{{STRUCTURE_1wur| PDB=1wur | SCENE= }}
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==Structure of GTP cyclohydrolase I Complexed with 8-oxo-dGTP==
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<StructureSection load='1wur' size='340' side='right'caption='[[1wur]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1wur]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WUR FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8DG:8-OXO-2-DEOXYGUANOSINE-5-TRIPHOSPHATE'>8DG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wur FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wur OCA], [https://pdbe.org/1wur PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wur RCSB], [https://www.ebi.ac.uk/pdbsum/1wur PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wur ProSAT], [https://www.topsan.org/Proteins/RSGI/1wur TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q5SH52_THET8 Q5SH52_THET8]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wu/1wur_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wur ConSurf].
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<div style="clear:both"></div>
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===Structure of GTP cyclohydrolase I Complexed with 8-oxo-dGTP===
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==See Also==
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*[[Cyclohydrolase 3D structures|Cyclohydrolase 3D structures]]
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{{ABSTRACT_PUBMED_16169877}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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[[1wur]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WUR OCA].
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==Reference==
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<ref group="xtra">PMID:016169877</ref><references group="xtra"/>
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[[Category: GTP cyclohydrolase I]]
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[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
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[[Category: Kuramitsu, S.]]
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[[Category: Kuramitsu S]]
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[[Category: Masui, R.]]
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[[Category: Masui R]]
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[[Category: Nakagawa, N.]]
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[[Category: Nakagawa N]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Tanaka Y]]
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[[Category: Tanaka, Y.]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S.]]
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[[Category: Beta barrel]]
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[[Category: Hydrolase]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Protein-inhibitor complex]]
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[[Category: Pteridine]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rsgi]]
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[[Category: Structural genomic]]
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[[Category: Tetrahydrobiopterin]]
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Current revision

Structure of GTP cyclohydrolase I Complexed with 8-oxo-dGTP

PDB ID 1wur

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