This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1wxe

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:34, 13 March 2024) (edit) (undo)
 
(9 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1wxe.png|left|200px]]
 
-
<!--
+
==E.coli NAD Synthetase, AMP==
-
The line below this paragraph, containing "STRUCTURE_1wxe", creates the "Structure Box" on the page.
+
<StructureSection load='1wxe' size='340' side='right'caption='[[1wxe]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1wxe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WXE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WXE FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-
{{STRUCTURE_1wxe| PDB=1wxe | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wxe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wxe OCA], [https://pdbe.org/1wxe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wxe RCSB], [https://www.ebi.ac.uk/pdbsum/1wxe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wxe ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/NADE_ECOLI NADE_ECOLI] Catalyzes a key step in NAD biosynthesis, transforming deamido-NAD into NAD by a two-step reaction.
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wx/1wxe_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wxe ConSurf].
 +
<div style="clear:both"></div>
-
===E.coli NAD Synthetase, AMP===
+
==See Also==
-
 
+
*[[NAD synthase|NAD synthase]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_15699042}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 15699042 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_15699042}}
+
-
 
+
-
==About this Structure==
+
-
1WXE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WXE OCA].
+
-
 
+
-
==Reference==
+
-
Structures of Escherichia coli NAD synthetase with substrates and products reveal mechanistic rearrangements., Jauch R, Humm A, Huber R, Wahl MC, J Biol Chem. 2005 Apr 15;280(15):15131-40. Epub 2005 Feb 7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15699042 15699042]
+
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Huber, R.]]
+
[[Category: Huber R]]
-
[[Category: Humm, A.]]
+
[[Category: Humm A]]
-
[[Category: Jauch, R.]]
+
[[Category: Jauch R]]
-
[[Category: Wahl, M C.]]
+
[[Category: Wahl MC]]
-
[[Category: E coli]]
+
-
[[Category: Nad]]
+
-
[[Category: Nade]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 13:35:50 2008''
+

Current revision

E.coli NAD Synthetase, AMP

PDB ID 1wxe

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1wxe"
Personal tools