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1wz3
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:1wz3.png|left|200px]] | ||
| - | < | + | ==The crystal structure of plant ATG12== |
| - | + | <StructureSection load='1wz3' size='340' side='right'caption='[[1wz3]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[1wz3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WZ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WZ3 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wz3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wz3 OCA], [https://pdbe.org/1wz3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wz3 RCSB], [https://www.ebi.ac.uk/pdbsum/1wz3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wz3 ProSAT]</span></td></tr> | |
| - | + | </table> | |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/AT12B_ARATH AT12B_ARATH] Ubiquitin-like protein involved in cytoplasm to vacuole transport (Cvt) and autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. ATG12/ATG5 conjugate has an essential role in plant nutrient recycling. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wz/1wz3_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wz3 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Autophagy-related protein 3D structures|Autophagy-related protein 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
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[[Category: Arabidopsis thaliana]] | [[Category: Arabidopsis thaliana]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Fujioka | + | [[Category: Fujioka Y]] |
| - | [[Category: Inagaki | + | [[Category: Inagaki F]] |
| - | [[Category: Ohsumi | + | [[Category: Ohsumi Y]] |
| - | [[Category: Suzuki | + | [[Category: Suzuki NN]] |
| - | [[Category: Yoshimoto | + | [[Category: Yoshimoto K]] |
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Current revision
The crystal structure of plant ATG12
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