This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2adv

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px<br /><applet load="2adv" size="450" color="white" frame="true" align="right" spinBox="true" caption="2adv, resolution 2.244&Aring;" /> '''Crystal Structures ...)
Current revision (13:40, 13 March 2024) (edit) (undo)
 
(17 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2adv.gif|left|200px]]<br /><applet load="2adv" size="450" color="white" frame="true" align="right" spinBox="true"
 
-
caption="2adv, resolution 2.244&Aring;" />
 
-
'''Crystal Structures Of Glutaryl 7-Aminocephalosporanic Acid Acylase: mutational study of activation mechanism'''<br />
 
-
==About this Structure==
+
==Crystal Structures Of Glutaryl 7-Aminocephalosporanic Acid Acylase: mutational study of activation mechanism==
-
2ADV is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Pseudomonas_sp. Pseudomonas sp.]. Active as [http://en.wikipedia.org/wiki/Penicillin_amidase Penicillin amidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.11 3.5.1.11] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2ADV OCA].
+
<StructureSection load='2adv' size='340' side='right'caption='[[2adv]], [[Resolution|resolution]] 2.24&Aring;' scene=''>
-
[[Category: Penicillin amidase]]
+
== Structural highlights ==
-
[[Category: Protein complex]]
+
<table><tr><td colspan='2'>[[2adv]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_sp._GK16 Pseudomonas sp. GK16]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ADV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ADV FirstGlance]. <br>
-
[[Category: Pseudomonas sp.]]
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.244&#8491;</td></tr>
-
[[Category: Cho, K.J.]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2adv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2adv OCA], [https://pdbe.org/2adv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2adv RCSB], [https://www.ebi.ac.uk/pdbsum/2adv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2adv ProSAT]</span></td></tr>
-
[[Category: Kim, J.K.]]
+
</table>
-
[[Category: Kim, K.H.]]
+
== Function ==
-
[[Category: Kim, S.H.]]
+
[https://www.uniprot.org/uniprot/G7AC_PSEU7 G7AC_PSEU7] Catalyzes the deacylation of 7 beta-(4-carboxybutanamido)cephalosporanic acid (glutaryl-7-aminocephalosporanic acid or GL-7-ACA) to 7-aminocephalosporanic acid (7-ACA).<ref>PMID:2993240</ref>
-
[[Category: Park, S.S.]]
+
== Evolutionary Conservation ==
-
[[Category: Ryu, E.K.]]
+
[[Image:Consurf_key_small.gif|200px|right]]
-
[[Category: Shin, H.J.]]
+
Check<jmol>
-
[[Category: Yang, I.S.]]
+
<jmolCheckbox>
-
[[Category: autoproteolysis]]
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ad/2adv_consurf.spt"</scriptWhenChecked>
-
[[Category: cephalosporin acylase]]
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
[[Category: intermediate structure]]
+
<text>to colour the structure by Evolutionary Conservation</text>
-
[[Category: precursor activation]]
+
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2adv ConSurf].
 +
<div style="clear:both"></div>
-
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 08:04:04 2007''
+
==See Also==
 +
*[[Cephalosporin acylase 3D structures|Cephalosporin acylase 3D structures]]
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
 +
[[Category: Pseudomonas sp. GK16]]
 +
[[Category: Cho KJ]]
 +
[[Category: Kim JK]]
 +
[[Category: Kim KH]]
 +
[[Category: Kim SH]]
 +
[[Category: Park SS]]
 +
[[Category: Ryu EK]]
 +
[[Category: Shin HJ]]
 +
[[Category: Yang IS]]

Current revision

Crystal Structures Of Glutaryl 7-Aminocephalosporanic Acid Acylase: mutational study of activation mechanism

PDB ID 2adv

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2adv"
Personal tools