This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2aw5

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:42, 13 March 2024) (edit) (undo)
 
(12 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2aw5.gif|left|200px]]
 
-
{{Structure
+
==Crystal structure of a human malic enzyme==
-
|PDB= 2aw5 |SIZE=350|CAPTION= <scene name='initialview01'>2aw5</scene>, resolution 2.50&Aring;
+
<StructureSection load='2aw5' size='340' side='right'caption='[[2aw5]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND=
+
<table><tr><td colspan='2'>[[2aw5]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AW5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AW5 FirstGlance]. <br>
-
|ACTIVITY= [http://en.wikipedia.org/wiki/Malate_dehydrogenase_(oxaloacetate-decarboxylating)_(NADP(+)) Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.40 1.1.1.40]
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-
|GENE=
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2aw5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2aw5 OCA], [https://pdbe.org/2aw5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2aw5 RCSB], [https://www.ebi.ac.uk/pdbsum/2aw5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2aw5 ProSAT]</span></td></tr>
-
}}
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/MAOX_HUMAN MAOX_HUMAN]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aw/2aw5_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2aw5 ConSurf].
 +
<div style="clear:both"></div>
-
'''Crystal structure of a human malic enzyme'''
+
==See Also==
-
 
+
*[[NADP-dependent malic enzyme|NADP-dependent malic enzyme]]
-
 
+
__TOC__
-
==About this Structure==
+
</StructureSection>
-
2AW5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AW5 OCA].
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+))]]
+
[[Category: Large Structures]]
-
[[Category: Single protein]]
+
[[Category: Arrowsmith C]]
-
[[Category: Arrowsmith, C.]]
+
[[Category: Berridge G]]
-
[[Category: Berridge, G.]]
+
[[Category: Bray J]]
-
[[Category: Bray, J.]]
+
[[Category: Edwards A]]
-
[[Category: Delft, F von.]]
+
[[Category: Gileadi O]]
-
[[Category: Edwards, A.]]
+
[[Category: Oppermann U]]
-
[[Category: Gileadi, O.]]
+
[[Category: Papagrigoriou E]]
-
[[Category: Oppermann, U.]]
+
[[Category: Smee C]]
-
[[Category: Papagrigoriou, E.]]
+
[[Category: Sundstrom M]]
-
[[Category: SGC, Structural Genomics Consortium.]]
+
[[Category: Weigelt J]]
-
[[Category: Smee, C.]]
+
[[Category: Von Delft F]]
-
[[Category: Sundstrom, M.]]
+
-
[[Category: Weigelt, J.]]
+
-
[[Category: rossmann fold]]
+
-
[[Category: sgc]]
+
-
[[Category: structural genomic]]
+
-
[[Category: structural genomics consortium]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:54:31 2008''
+

Current revision

Crystal structure of a human malic enzyme

PDB ID 2aw5

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools