2bd0

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{{Seed}}
 
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[[Image:2bd0.png|left|200px]]
 
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==Chlorobium tepidum Sepiapterin Reductase complexed with NADP and Sepiapterin==
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The line below this paragraph, containing "STRUCTURE_2bd0", creates the "Structure Box" on the page.
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<StructureSection load='2bd0' size='340' side='right'caption='[[2bd0]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2bd0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlorobaculum_tepidum_TLS Chlorobaculum tepidum TLS]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BD0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BD0 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BIO:BIOPTERIN'>BIO</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
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{{STRUCTURE_2bd0| PDB=2bd0 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bd0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bd0 OCA], [https://pdbe.org/2bd0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bd0 RCSB], [https://www.ebi.ac.uk/pdbsum/2bd0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bd0 ProSAT]</span></td></tr>
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</table>
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===Chlorobium tepidum Sepiapterin Reductase complexed with NADP and Sepiapterin===
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== Function ==
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[https://www.uniprot.org/uniprot/SPRE_CHLTE SPRE_CHLTE] Catalyzes the final reductions in tetra-hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin.<ref>PMID:10333495</ref> <ref>PMID:15621425</ref> <ref>PMID:18542834</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_16308317}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 16308317 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bd/2bd0_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_16308317}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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2BD0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Chlorobaculum_tepidum Chlorobaculum tepidum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BD0 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bd0 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Structure of Chlorobium tepidum sepiapterin reductase complex reveals the novel substrate binding mode for stereospecific production of L-threo-tetrahydrobiopterin., Supangat S, Seo KH, Choi YK, Park YS, Son D, Han CD, Lee KH, J Biol Chem. 2006 Jan 27;281(4):2249-56. Epub 2005 Nov 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16308317 16308317]
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<references/>
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[[Category: Chlorobaculum tepidum]]
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__TOC__
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[[Category: Sepiapterin reductase]]
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</StructureSection>
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[[Category: Single protein]]
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[[Category: Chlorobaculum tepidum TLS]]
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[[Category: Choi, Y K.]]
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[[Category: Large Structures]]
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[[Category: Lee, K H.]]
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[[Category: Choi YK]]
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[[Category: Park, Y S.]]
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[[Category: Lee KH]]
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[[Category: Seo, K H.]]
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[[Category: Park YS]]
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[[Category: Supangat, S.]]
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[[Category: Seo KH]]
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[[Category: Chlorobium tepidum]]
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[[Category: Supangat S]]
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[[Category: Sepiapterin reductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 20:26:39 2008''
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Current revision

Chlorobium tepidum Sepiapterin Reductase complexed with NADP and Sepiapterin

PDB ID 2bd0

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