This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2cya
From Proteopedia
(Difference between revisions)
| (9 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:2cya.png|left|200px]] | ||
| - | + | ==Crystal structure of tyrosyl-tRNA synthetase from Aeropyrum pernix== | |
| - | + | <StructureSection load='2cya' size='340' side='right'caption='[[2cya]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2cya]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aeropyrum_pernix Aeropyrum pernix]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CYA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CYA FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cya FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cya OCA], [https://pdbe.org/2cya PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cya RCSB], [https://www.ebi.ac.uk/pdbsum/2cya PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cya ProSAT], [https://www.topsan.org/Proteins/RSGI/2cya TOPSAN]</span></td></tr> |
| - | [[2cya]] is a 1 chain structure | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SYY_AERPE SYY_AERPE] Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).[HAMAP-Rule:MF_02009] | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/cy/2cya_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2cya ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Aminoacyl tRNA | + | *[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | ||
[[Category: Aeropyrum pernix]] | [[Category: Aeropyrum pernix]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Bessho | + | [[Category: Bessho Y]] |
| - | [[Category: Chen | + | [[Category: Chen L]] |
| - | [[Category: Kobayashi | + | [[Category: Kobayashi T]] |
| - | [[Category: Kuramitsu | + | [[Category: Kuramitsu S]] |
| - | [[Category: Kuratani | + | [[Category: Kuratani M]] |
| - | [[Category: Kuroishi | + | [[Category: Kuroishi C]] |
| - | [[Category: Liu | + | [[Category: Liu ZJ]] |
| - | [[Category: Murayama | + | [[Category: Murayama K]] |
| - | + | [[Category: Sakai H]] | |
| - | [[Category: Sakai | + | [[Category: Sekine SI]] |
| - | [[Category: Sekine | + | [[Category: Shirouzu M]] |
| - | [[Category: Shirouzu | + | [[Category: Takahashi M]] |
| - | [[Category: Takahashi | + | [[Category: Terada T]] |
| - | [[Category: Terada | + | [[Category: Wang BC]] |
| - | [[Category: Wang | + | [[Category: Yanagisawa T]] |
| - | [[Category: Yanagisawa | + | [[Category: Yokoyama S]] |
| - | [[Category: Yokoyama | + | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal structure of tyrosyl-tRNA synthetase from Aeropyrum pernix
| |||||||||||
Categories: Aeropyrum pernix | Large Structures | Bessho Y | Chen L | Kobayashi T | Kuramitsu S | Kuratani M | Kuroishi C | Liu ZJ | Murayama K | Sakai H | Sekine SI | Shirouzu M | Takahashi M | Terada T | Wang BC | Yanagisawa T | Yokoyama S
