2d1v

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[[Image:2d1v.jpg|left|200px]]
 
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{{Structure
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==Crystal structure of DNA-binding domain of Bacillus subtilis YycF==
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|PDB= 2d1v |SIZE=350|CAPTION= <scene name='initialview01'>2d1v</scene>, resolution 2.4&Aring;
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<StructureSection load='2d1v' size='340' side='right'caption='[[2d1v]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[2d1v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D1V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D1V FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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|GENE= yycF ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d1v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d1v OCA], [https://pdbe.org/2d1v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d1v RCSB], [https://www.ebi.ac.uk/pdbsum/2d1v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d1v ProSAT]</span></td></tr>
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}}
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</table>
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== Function ==
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'''Crystal structure of DNA-binding domain of Bacillus subtilis YycF'''
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[https://www.uniprot.org/uniprot/WALR_BACSU WALR_BACSU] Member of the two-component regulatory system WalK/WalR involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Binds to the ftsAZ P1 promoter sequence in vitro. WalR has been shown to directly bind to the regulatory regions of yocH, ykvT, tagAB/tagDEF. Activates cwlO, lytE and ydjM and represses yoeB and yjeA.<ref>PMID:10878122</ref> <ref>PMID:12950927</ref> <ref>PMID:17581128</ref> <ref>PMID:9829949</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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2D1V is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D1V OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d1/2d1v_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d1v ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Okada, A.]]
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[[Category: Okada A]]
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[[Category: Okajima, T.]]
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[[Category: Okajima T]]
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[[Category: Tanizawa, K.]]
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[[Category: Tanizawa K]]
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[[Category: Utsumi, R.]]
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[[Category: Utsumi R]]
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[[Category: Watanabe, T.]]
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[[Category: Watanabe T]]
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[[Category: Yamamoto, K.]]
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[[Category: Yamamoto K]]
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[[Category: dna-binding domain]]
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[[Category: helix-turn-helix motif]]
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[[Category: response regulator]]
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[[Category: two-component system]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:22:17 2008''
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Current revision

Crystal structure of DNA-binding domain of Bacillus subtilis YycF

PDB ID 2d1v

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