2d1v

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{{Seed}}
 
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[[Image:2d1v.png|left|200px]]
 
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==Crystal structure of DNA-binding domain of Bacillus subtilis YycF==
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The line below this paragraph, containing "STRUCTURE_2d1v", creates the "Structure Box" on the page.
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<StructureSection load='2d1v' size='340' side='right'caption='[[2d1v]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2d1v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D1V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D1V FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d1v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d1v OCA], [https://pdbe.org/2d1v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d1v RCSB], [https://www.ebi.ac.uk/pdbsum/2d1v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d1v ProSAT]</span></td></tr>
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{{STRUCTURE_2d1v| PDB=2d1v | SCENE= }}
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</table>
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== Function ==
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===Crystal structure of DNA-binding domain of Bacillus subtilis YycF===
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[https://www.uniprot.org/uniprot/WALR_BACSU WALR_BACSU] Member of the two-component regulatory system WalK/WalR involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Binds to the ftsAZ P1 promoter sequence in vitro. WalR has been shown to directly bind to the regulatory regions of yocH, ykvT, tagAB/tagDEF. Activates cwlO, lytE and ydjM and represses yoeB and yjeA.<ref>PMID:10878122</ref> <ref>PMID:12950927</ref> <ref>PMID:17581128</ref> <ref>PMID:9829949</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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(as it appears on PubMed at http://www.pubmed.gov), where 18789936 is the PubMed ID number.
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/d1/2d1v_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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{{ABSTRACT_PUBMED_18789936}}
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==About this Structure==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2d1v ConSurf].
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2D1V is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D1V OCA].
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<div style="clear:both"></div>
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== References ==
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==Reference==
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<references/>
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Response regulator YycF essential for bacterial growth: X-ray crystal structure of the DNA-binding domain and its PhoB-like DNA recognition motif., Okajima T, Doi A, Okada A, Gotoh Y, Tanizawa K, Utsumi R, FEBS Lett. 2008 Oct 15;582(23-24):3434-8. Epub 2008 Sep 26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18789936 18789936]
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__TOC__
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</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Okada, A.]]
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[[Category: Large Structures]]
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[[Category: Okajima, T.]]
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[[Category: Okada A]]
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[[Category: Tanizawa, K.]]
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[[Category: Okajima T]]
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[[Category: Utsumi, R.]]
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[[Category: Tanizawa K]]
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[[Category: Watanabe, T.]]
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[[Category: Utsumi R]]
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[[Category: Yamamoto, K.]]
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[[Category: Watanabe T]]
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[[Category: Dna-binding domain]]
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[[Category: Yamamoto K]]
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[[Category: Helix-turn-helix motif]]
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[[Category: Response regulator]]
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[[Category: Transcription]]
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[[Category: Two-component system]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 10 15:13:47 2008''
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Current revision

Crystal structure of DNA-binding domain of Bacillus subtilis YycF

PDB ID 2d1v

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