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2dst

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==Crystal Structure Analysis of TT1977==
==Crystal Structure Analysis of TT1977==
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<StructureSection load='2dst' size='340' side='right' caption='[[2dst]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='2dst' size='340' side='right'caption='[[2dst]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2dst]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DST OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DST FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2dst]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DST OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DST FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cyd|2cyd]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dst FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dst OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2dst RCSB], [http://www.ebi.ac.uk/pdbsum/2dst PDBsum], [http://www.topsan.org/Proteins/RSGI/2dst TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dst FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dst OCA], [https://pdbe.org/2dst PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dst RCSB], [https://www.ebi.ac.uk/pdbsum/2dst PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dst ProSAT], [https://www.topsan.org/Proteins/RSGI/2dst TOPSAN]</span></td></tr>
</table>
</table>
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<div style="background-color:#fffaf0;">
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== Function ==
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== Publication Abstract from PubMed ==
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[https://www.uniprot.org/uniprot/Q5SI36_THET8 Q5SI36_THET8]
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The gene encoding TTHA1544 is a singleton found in the Thermus thermophilus HB8 genome and encodes a 131-amino-acid protein. The crystal structure of TTHA1544 has been determined at 2.0 A resolution by the single-wavelength anomalous dispersion method in order to elucidate its function. There are two molecules in the asymmetric unit. Each molecule consists of four alpha-helices and six beta-strands, with the beta-strands composing a central beta-sheet. A structural homology search revealed that the overall structure of TTHA1544 resembles the alpha/beta-hydrolase fold, although TTHA1544 lacks the catalytic residues of a hydrolase. These results suggest that TTHA1544 represents the minimized alpha/beta-hydrolase fold and that an additional component would be required for its activity.
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Structure of the minimized alpha/beta-hydrolase fold protein from Thermus thermophilus HB8.,Xie Y, Takemoto C, Kishishita S, Uchikubo-Kamo T, Murayama K, Chen L, Liu ZJ, Wang BC, Manzoku M, Ebihara A, Kuramitsu S, Shirouzu M, Yokoyama S Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Dec 1;63(Pt, 12):993-7. Epub 2007 Nov 30. PMID:18084077<ref>PMID:18084077</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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== References ==
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<references/>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
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[[Category: Chen, L]]
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[[Category: Chen L]]
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[[Category: Kishishita, S]]
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[[Category: Kishishita S]]
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[[Category: Liu, Z J]]
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[[Category: Liu ZJ]]
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[[Category: Murayama, K]]
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[[Category: Murayama K]]
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[[Category: Structural genomic]]
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[[Category: Shirouzu M]]
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[[Category: Shirouzu, M]]
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[[Category: Wang BC]]
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[[Category: Wang, B C]]
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[[Category: Xie Y]]
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[[Category: Xie, Y]]
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[[Category: Conserved hypothetical protein]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Rsgi]]
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[[Category: Unknown function]]
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Crystal Structure Analysis of TT1977

PDB ID 2dst

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