2dx8
From Proteopedia
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| - | [[Image:2dx8.jpg|left|200px]]<br /><applet load="2dx8" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2dx8, resolution 2.70Å" /> | ||
| - | '''Crystal Structure Analysis of the PHD domain of the Transcription Coactivator Pygophus'''<br /> | ||
| - | == | + | ==Crystal Structure Analysis of the PHD domain of the Transcription Coactivator Pygophus== |
| - | + | <StructureSection load='2dx8' size='340' side='right'caption='[[2dx8]], [[Resolution|resolution]] 2.70Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2dx8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DX8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DX8 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dx8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dx8 OCA], [https://pdbe.org/2dx8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dx8 RCSB], [https://www.ebi.ac.uk/pdbsum/2dx8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dx8 ProSAT], [https://www.topsan.org/Proteins/RSGI/2dx8 TOPSAN]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PYGO1_MOUSE PYGO1_MOUSE] Involved in signal transduction through the Wnt pathway (By similarity). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dx/2dx8_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dx8 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
| - | + | [[Category: Padmanabhan B]] | |
| - | [[Category: Padmanabhan | + | [[Category: Yokoyama S]] |
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| - | [[Category: Yokoyama | + | |
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Current revision
Crystal Structure Analysis of the PHD domain of the Transcription Coactivator Pygophus
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