2dzo
From Proteopedia
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| - | [[Image:2dzo.gif|left|200px]]<br /><applet load="2dzo" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2dzo, resolution 3.00Å" /> | ||
| - | '''Crystal structure analysis of yeast Nas6p complexed with the proteasome subunit, rpt3'''<br /> | ||
| - | == | + | ==Crystal structure analysis of yeast Nas6p complexed with the proteasome subunit, rpt3== |
| - | + | <StructureSection load='2dzo' size='340' side='right'caption='[[2dzo]], [[Resolution|resolution]] 3.00Å' scene=''> | |
| - | [[ | + | == Structural highlights == |
| + | <table><tr><td colspan='2'>[[2dzo]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DZO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DZO FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dzo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dzo OCA], [https://pdbe.org/2dzo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dzo RCSB], [https://www.ebi.ac.uk/pdbsum/2dzo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dzo ProSAT], [https://www.topsan.org/Proteins/RSGI/2dzo TOPSAN]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PSD10_YEAST PSD10_YEAST] Acts as a chaperone during the assembly of the 26S proteasome, specifically of the 19S regulatory complex (RC) and appears to have an overlapping role with RPN14.<ref>PMID:19412159</ref> <ref>PMID:19446322</ref> <ref>PMID:9714768</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dz/2dzo_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2dzo ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
| - | [[Category: Nakamura | + | [[Category: Nakamura Y]] |
| - | [[Category: Padmanabhan | + | [[Category: Padmanabhan B]] |
| - | + | [[Category: Yokoyama S]] | |
| - | [[Category: Yokoyama | + | |
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Current revision
Crystal structure analysis of yeast Nas6p complexed with the proteasome subunit, rpt3
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