2efc

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(New page: 200px<br /><applet load="2efc" size="350" color="white" frame="true" align="right" spinBox="true" caption="2efc, resolution 2.09&Aring;" /> '''Ara7-GDP/AtVps9a'''<...)
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[[Image:2efc.jpg|left|200px]]<br /><applet load="2efc" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="2efc, resolution 2.09&Aring;" />
 
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'''Ara7-GDP/AtVps9a'''<br />
 
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==About this Structure==
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==Ara7-GDP/AtVps9a==
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2EFC is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana] with <scene name='pdbligand=GDP:'>GDP</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Sites: <scene name='pdbsite=AC1:Gdp+Binding+Site+For+Residue+B+1200'>AC1</scene> and <scene name='pdbsite=AC2:Gdp+Binding+Site+For+Residue+D+2200'>AC2</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EFC OCA].
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<StructureSection load='2efc' size='340' side='right'caption='[[2efc]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2efc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EFC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EFC FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.09&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2efc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2efc OCA], [https://pdbe.org/2efc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2efc RCSB], [https://www.ebi.ac.uk/pdbsum/2efc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2efc ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/VPS9A_ARATH VPS9A_ARATH] Functions as guanine nucleotide exchange factor (GEF) for Rab small GTPases. Activates specifically RABF1, RABF2A and RABF2B proteins. Required for early stages of embryogenesis, cytokinesis, embryogenesis, and organ development. Is essential for the establishment or maintenance of the polar localization of the auxin efflux carrier PIN1.<ref>PMID:18055610</ref> <ref>PMID:20833725</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ef/2efc_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2efc ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
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[[Category: Protein complex]]
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[[Category: Large Structures]]
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[[Category: Goh, T.]]
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[[Category: Goh T]]
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[[Category: Ihara, K.]]
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[[Category: Ihara K]]
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[[Category: Ito, E.]]
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[[Category: Ito E]]
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[[Category: Nakano, A.]]
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[[Category: Nakano A]]
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[[Category: Sunada, M.]]
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[[Category: Sunada M]]
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[[Category: Ueda, T.]]
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[[Category: Ueda T]]
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[[Category: Uejima, T.]]
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[[Category: Uejima T]]
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[[Category: Wakatsuki, S.]]
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[[Category: Wakatsuki S]]
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[[Category: GDP]]
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[[Category: gef]]
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[[Category: gtpase]]
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[[Category: nucleotide]]
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[[Category: rab5]]
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[[Category: transport protein]]
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[[Category: vps9]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 27 07:58:14 2008''
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Current revision

Ara7-GDP/AtVps9a

PDB ID 2efc

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