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2gaz

From Proteopedia

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{{Seed}}
 
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[[Image:2gaz.png|left|200px]]
 
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==Mycobacterial lipoglycan presentation by CD1d==
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The line below this paragraph, containing "STRUCTURE_2gaz", creates the "Structure Box" on the page.
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<StructureSection load='2gaz' size='340' side='right'caption='[[2gaz]], [[Resolution|resolution]] 2.61&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2gaz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GAZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2GAZ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.61&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=XPX:(2R)-3-[(HYDROXY{[(2R,3R,5S,6R)-3,4,5-TRIHYDROXY-2,6-BIS(ALPHA-D-MANNOPYRANOSYLOXY)CYCLOHEXYL]OXY}PHOSPHORYL)OXY]PROPANE-1,2-DIYL+DIHEXADECANOATE'>XPX</scene></td></tr>
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{{STRUCTURE_2gaz| PDB=2gaz | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2gaz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gaz OCA], [https://pdbe.org/2gaz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2gaz RCSB], [https://www.ebi.ac.uk/pdbsum/2gaz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2gaz ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CD1D1_MOUSE CD1D1_MOUSE] Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.<ref>PMID:11754812</ref> <ref>PMID:16314439</ref> <ref>PMID:16007091</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ga/2gaz_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2gaz ConSurf].
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<div style="clear:both"></div>
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===Mycobacterial lipoglycan presentation by CD1d===
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==See Also==
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*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
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*[[CD1|CD1]]
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== References ==
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The line below this paragraph, {{ABSTRACT_PUBMED_16982895}}, adds the Publication Abstract to the page
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<references/>
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(as it appears on PubMed at http://www.pubmed.gov), where 16982895 is the PubMed ID number.
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__TOC__
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</StructureSection>
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{{ABSTRACT_PUBMED_16982895}}
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[[Category: Large Structures]]
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==About this Structure==
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2GAZ is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GAZ OCA].
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==Reference==
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Structural characterization of mycobacterial phosphatidylinositol mannoside binding to mouse CD1d., Zajonc DM, Ainge GD, Painter GF, Severn WB, Wilson IA, J Immunol. 2006 Oct 1;177(7):4577-83. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16982895 16982895]
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[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Protein complex]]
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[[Category: Zajonc DM]]
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[[Category: Zajonc, D M.]]
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[[Category: Cd1]]
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[[Category: Lipid antigen presentation]]
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[[Category: Mycobacteria]]
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[[Category: Nkt cell]]
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[[Category: Tcr]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 04:15:21 2008''
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Current revision

Mycobacterial lipoglycan presentation by CD1d

PDB ID 2gaz

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