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2h8g

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[[Image:2h8g.gif|left|200px]]
 
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==5'-Methylthioadenosine Nucleosidase from Arabidopsis thaliana==
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The line below this paragraph, containing "STRUCTURE_2h8g", creates the "Structure Box" on the page.
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<StructureSection load='2h8g' size='340' side='right'caption='[[2h8g]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2h8g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H8G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2H8G FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene></td></tr>
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{{STRUCTURE_2h8g| PDB=2h8g | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2h8g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2h8g OCA], [https://pdbe.org/2h8g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2h8g RCSB], [https://www.ebi.ac.uk/pdbsum/2h8g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2h8g ProSAT]</span></td></tr>
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</table>
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'''5'-Methylthioadenosine Nucleosidase from Arabidopsis thaliana'''
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== Function ==
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[https://www.uniprot.org/uniprot/MTN1_ARATH MTN1_ARATH] Enzyme of the methionine cycle that catalyzes the irreversible cleavage of the glycosidic bond in 5'-methylthioadenosine (MTA) to adenine and 5'-methylthioribose. Contributes to the maintenance of AdoMet homeostasis and is required to sustain high rates of ethylene synthesis. Inactive towards S-adenosylhomocysteine (SAH/AdoHcy).<ref>PMID:17144895</ref> <ref>PMID:18342331</ref> <ref>PMID:20345605</ref>
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== Evolutionary Conservation ==
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==About this Structure==
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[[Image:Consurf_key_small.gif|200px|right]]
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2H8G is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H8G OCA].
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Check<jmol>
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<jmolCheckbox>
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==Reference==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h8/2h8g_consurf.spt"</scriptWhenChecked>
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Crystal structure of 5'-methylthioadenosine nucleosidase from Arabidopsis thaliana at 1.5-A resolution., Park EY, Oh SI, Nam MJ, Shin JS, Kim KN, Song HK, Proteins. 2006 Nov 1;65(2):519-23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16909418 16909418]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2h8g ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
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[[Category: Methylthioadenosine nucleosidase]]
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Kim KN]]
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[[Category: Kim, K N.]]
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[[Category: Nam MJ]]
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[[Category: Nam, M J.]]
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[[Category: Oh SI]]
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[[Category: Oh, S I.]]
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[[Category: Park EY]]
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[[Category: Park, E Y.]]
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[[Category: Shin JS]]
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[[Category: Shin, J S.]]
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[[Category: Song HK]]
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[[Category: Song, H K.]]
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[[Category: Protein-adenine complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 05:59:27 2008''
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Current revision

5'-Methylthioadenosine Nucleosidase from Arabidopsis thaliana

PDB ID 2h8g

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