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2qhv

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==Structural Basis of Octanoic Acid Recognition by Lipoate-Protein Ligase B==
==Structural Basis of Octanoic Acid Recognition by Lipoate-Protein Ligase B==
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<StructureSection load='2qhv' size='340' side='right' caption='[[2qhv]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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<StructureSection load='2qhv' size='340' side='right'caption='[[2qhv]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2qhv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QHV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2QHV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2qhv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QHV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QHV FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OC9:OCTAN-1-OL'>OC9</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2qhs|2qhs]], [[2qht|2qht]], [[2qhu|2qhu]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OC9:OCTAN-1-OL'>OC9</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TTC 1746 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qhv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qhv OCA], [https://pdbe.org/2qhv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qhv RCSB], [https://www.ebi.ac.uk/pdbsum/2qhv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qhv ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qhv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qhv OCA], [http://pdbe.org/2qhv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qhv RCSB], [http://www.ebi.ac.uk/pdbsum/2qhv PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LIPB_THET8 LIPB_THET8]] Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity).
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[https://www.uniprot.org/uniprot/LIPB_THET8 LIPB_THET8] Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qh/2qhv_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qh/2qhv_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Thet8]]
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[[Category: Large Structures]]
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[[Category: Kim, D J]]
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[[Category: Thermus thermophilus HB8]]
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[[Category: Kim, H S]]
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[[Category: Kim DJ]]
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[[Category: Kim, K H]]
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[[Category: Kim HS]]
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[[Category: Lee, H H]]
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[[Category: Kim KH]]
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[[Category: Lee, S J]]
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[[Category: Lee HH]]
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[[Category: Suh, S W]]
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[[Category: Lee SJ]]
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[[Category: Yoon, H J]]
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[[Category: Suh SW]]
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[[Category: Globular protein]]
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[[Category: Yoon HJ]]
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[[Category: Transferase]]
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Current revision

Structural Basis of Octanoic Acid Recognition by Lipoate-Protein Ligase B

PDB ID 2qhv

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