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2qht

From Proteopedia

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[[Image:2qht.jpg|left|200px]]
 
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{{Structure
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==Structural Basis of Octanoic Acid Recognition by Lipoate-Protein Ligase B==
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|PDB= 2qht |SIZE=350|CAPTION= <scene name='initialview01'>2qht</scene>, resolution 1.500&Aring;
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<StructureSection load='2qht' size='340' side='right'caption='[[2qht]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[2qht]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QHT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2QHT FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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|GENE= TTC 1746 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 Thermus thermophilus])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2qht FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qht OCA], [https://pdbe.org/2qht PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2qht RCSB], [https://www.ebi.ac.uk/pdbsum/2qht PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2qht ProSAT]</span></td></tr>
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|DOMAIN=
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</table>
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|RELATEDENTRY=[[2qhs|2QHS]], [[2qhu|2QHU]], [[2qhv|2QHV]]
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== Function ==
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2qht FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qht OCA], [http://www.ebi.ac.uk/pdbsum/2qht PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2qht RCSB]</span>
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[https://www.uniprot.org/uniprot/LIPB_THET8 LIPB_THET8] Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity).
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}}
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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'''Structural Basis of Octanoic Acid Recognition by Lipoate-Protein Ligase B'''
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/qh/2qht_consurf.spt"</scriptWhenChecked>
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==About this Structure==
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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2QHT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QHT OCA].
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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==Reference==
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2qht ConSurf].
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Structural basis of octanoic acid recognition by lipoate-protein ligase B., Kim do J, Lee SJ, Kim HS, Kim KH, Lee HH, Yoon HJ, Suh SW, Proteins. 2008 Mar;70(4):1620-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18076036 18076036]
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<div style="clear:both"></div>
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[[Category: Single protein]]
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__TOC__
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[[Category: Thermus thermophilus]]
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</StructureSection>
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[[Category: Kim, D J.]]
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[[Category: Large Structures]]
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[[Category: Kim, H S.]]
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[[Category: Thermus thermophilus HB8]]
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[[Category: Kim, K H.]]
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[[Category: Kim DJ]]
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[[Category: Lee, H H.]]
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[[Category: Kim HS]]
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[[Category: Lee, S J.]]
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[[Category: Kim KH]]
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[[Category: Suh, S W.]]
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[[Category: Lee HH]]
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[[Category: Yoon, H J.]]
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[[Category: Lee SJ]]
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[[Category: globular protein]]
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[[Category: Suh SW]]
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[[Category: transferase]]
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[[Category: Yoon HJ]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:49:29 2008''
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Current revision

Structural Basis of Octanoic Acid Recognition by Lipoate-Protein Ligase B

PDB ID 2qht

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