2rfo

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[[Image:2rfo.jpg|left|200px]]
 
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{{Structure
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==Crystral Structure of the nucleoporin Nic96==
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|PDB= 2rfo |SIZE=350|CAPTION= <scene name='initialview01'>2rfo</scene>, resolution 2.60&Aring;
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<StructureSection load='2rfo' size='340' side='right'caption='[[2rfo]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[2rfo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RFO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RFO FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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|GENE= NIC96 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rfo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rfo OCA], [https://pdbe.org/2rfo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rfo RCSB], [https://www.ebi.ac.uk/pdbsum/2rfo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rfo ProSAT]</span></td></tr>
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}}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NIC96_YEAST NIC96_YEAST] Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. NIC96, which is localized to the core of the NPC and the distal ring of the nuclear basket, is required for de novo assembly of NPCs. It is involved in nuclear GSP1 import.<ref>PMID:7828598</ref> <ref>PMID:8682855</ref> <ref>PMID:9017593</ref> <ref>PMID:10428845</ref> <ref>PMID:10617624</ref> <ref>PMID:11121302</ref> <ref>PMID:10806080</ref> <ref>PMID:11689687</ref> <ref>PMID:12403813</ref> <ref>PMID:12496130</ref> <ref>PMID:12730220</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rf/2rfo_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2rfo ConSurf].
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<div style="clear:both"></div>
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'''Crystral Structure of the nucleoporin Nic96'''
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==See Also==
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*[[Nucleoporin 3D structures|Nucleoporin 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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2RFO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RFO OCA].
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Single protein]]
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[[Category: Flemming D]]
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[[Category: Flemming, D.]]
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[[Category: Hurt E]]
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[[Category: Hurt, E.]]
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[[Category: Kunze K]]
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[[Category: Kunze, K.]]
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[[Category: Schrader N]]
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[[Category: Schrader, N.]]
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[[Category: Stelter P]]
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[[Category: Stelter, P.]]
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[[Category: Vetter IR]]
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[[Category: Vetter, I R.]]
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[[Category: alpha-alpha-superhelix]]
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[[Category: mrna transport]]
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[[Category: nuclear pore complex]]
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[[Category: nucleus]]
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[[Category: protein transport]]
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[[Category: structural protein]]
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[[Category: translocation]]
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[[Category: transport]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:35:43 2008''
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Current revision

Crystral Structure of the nucleoporin Nic96

PDB ID 2rfo

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