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2z15
From Proteopedia
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| - | [[Image:2z15.jpg|left|200px]]<br /><applet load="2z15" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2z15, resolution 2.30Å" /> | ||
| - | '''Crystal structure of human Tob1 protein'''<br /> | ||
| - | == | + | ==Crystal structure of human Tob1 protein== |
| - | + | <StructureSection load='2z15' size='340' side='right'caption='[[2z15]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2z15]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z15 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z15 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z15 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z15 OCA], [https://pdbe.org/2z15 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z15 RCSB], [https://www.ebi.ac.uk/pdbsum/2z15 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z15 ProSAT], [https://www.topsan.org/Proteins/RSGI/2z15 TOPSAN]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TOB1_HUMAN TOB1_HUMAN] Anti-proliferative protein that interacts with the erbB-2 receptor tyrosine kinase. May physically and/or functionally interact with protein-tyrosine kinase receptors. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z1/2z15_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z15 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Kigawa | + | [[Category: Kigawa T]] |
| - | [[Category: Kishishita | + | [[Category: Kishishita S]] |
| - | [[Category: Murayama | + | [[Category: Murayama K]] |
| - | [[Category: Nishino | + | [[Category: Nishino A]] |
| - | + | [[Category: Saito K]] | |
| - | [[Category: Saito | + | [[Category: Shirouzu M]] |
| - | [[Category: Shirouzu | + | [[Category: Terada T]] |
| - | [[Category: Terada | + | [[Category: Yokoyama S]] |
| - | [[Category: Yokoyama | + | |
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Current revision
Crystal structure of human Tob1 protein
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Categories: Homo sapiens | Large Structures | Kigawa T | Kishishita S | Murayama K | Nishino A | Saito K | Shirouzu M | Terada T | Yokoyama S
