This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2ziu

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:57, 13 March 2024) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2ziu.png|left|200px]]
 
-
<!--
+
==Crystal structure of the Mus81-Eme1 complex==
-
The line below this paragraph, containing "STRUCTURE_2ziu", creates the "Structure Box" on the page.
+
<StructureSection load='2ziu' size='340' side='right'caption='[[2ziu]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2ziu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Danio_rerio Danio rerio] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZIU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZIU FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ziu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ziu OCA], [https://pdbe.org/2ziu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ziu RCSB], [https://www.ebi.ac.uk/pdbsum/2ziu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ziu ProSAT]</span></td></tr>
-
{{STRUCTURE_2ziu| PDB=2ziu | SCENE= }}
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/MUS81_DANRE MUS81_DANRE] Interacts with eme1 and eme2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks (By similarity).
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zi/2ziu_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ziu ConSurf].
 +
<div style="clear:both"></div>
-
===Crystal structure of the Mus81-Eme1 complex===
+
==See Also==
-
 
+
*[[Endonuclease 3D structures|Endonuclease 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_18413719}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 18413719 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_18413719}}
+
-
 
+
-
==About this Structure==
+
-
2ZIU is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Danio_rerio Danio rerio] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZIU OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:18413719</ref><references group="xtra"/>
+
[[Category: Danio rerio]]
[[Category: Danio rerio]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Chang, J H.]]
+
[[Category: Large Structures]]
-
[[Category: Cho, Y.]]
+
[[Category: Chang JH]]
-
[[Category: Choi, J M.]]
+
[[Category: Cho Y]]
-
[[Category: Kim, J J.]]
+
[[Category: Choi JM]]
-
[[Category: Lee, J H.]]
+
[[Category: Kim JJ]]
-
[[Category: Alternative splicing]]
+
[[Category: Lee JH]]
-
[[Category: Dna damage]]
+
-
[[Category: Dna recombination]]
+
-
[[Category: Dna repair]]
+
-
[[Category: Endonuclease]]
+
-
[[Category: Helix-hairpin-helix]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Magnesium]]
+
-
[[Category: Metal-binding]]
+
-
[[Category: Nuclease]]
+
-
[[Category: Nucleus]]
+
-
[[Category: Phosphoprotein]]
+
-
[[Category: Polymorphism]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 10:21:53 2009''
+

Current revision

Crystal structure of the Mus81-Eme1 complex

PDB ID 2ziu

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2ziu"
Personal tools