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3aii

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[[Image:3aii.png|left|200px]]
 
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{{STRUCTURE_3aii| PDB=3aii | SCENE= }}
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==Archaeal non-discriminating glutamyl-tRNA synthetase from Methanothermobacter thermautotrophicus==
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<StructureSection load='3aii' size='340' side='right'caption='[[3aii]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
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===Archaeal non-discriminating glutamyl-tRNA synthetase from Methanothermobacter thermautotrophicus===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3aii]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus_str._Delta_H Methanothermobacter thermautotrophicus str. Delta H]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AII OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AII FirstGlance]. <br>
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{{ABSTRACT_PUBMED_20601684}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3aii FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3aii OCA], [https://pdbe.org/3aii PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3aii RCSB], [https://www.ebi.ac.uk/pdbsum/3aii PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3aii ProSAT]</span></td></tr>
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[[3aii]] is a 1 chain structure of [[Aminoacyl tRNA Synthetase]] with sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AII OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SYE_METTH SYE_METTH] Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).[HAMAP-Rule:MF_00022]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ai/3aii_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3aii ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Aminoacyl tRNA Synthetase|Aminoacyl tRNA Synthetase]]
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*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:020601684</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Glutamate--tRNA ligase]]
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[[Category: Methanothermobacter thermautotrophicus str. Delta H]]
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[[Category: Methanothermobacter thermautotrophicus]]
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[[Category: Ishitani R]]
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[[Category: Ishitani, R.]]
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[[Category: Nureki O]]
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[[Category: Nureki, O.]]
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[[Category: Amino-acyl trna synthetase]]
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[[Category: Ligase]]
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Current revision

Archaeal non-discriminating glutamyl-tRNA synthetase from Methanothermobacter thermautotrophicus

PDB ID 3aii

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