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3al0

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[[Image:3al0.png|left|200px]]
 
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{{STRUCTURE_3al0| PDB=3al0 | SCENE= }}
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==Crystal structure of the glutamine transamidosome from Thermotoga maritima in the glutamylation state.==
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<StructureSection load='3al0' size='340' side='right'caption='[[3al0]], [[Resolution|resolution]] 3.37&Aring;' scene=''>
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===Crystal structure of the glutamine transamidosome from Thermotoga maritima in the glutamylation state.===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3al0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AL0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AL0 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_20882017}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.368&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GSU:O5-(L-GLUTAMYL-SULFAMOYL)-ADENOSINE'>GSU</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3al0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3al0 OCA], [https://pdbe.org/3al0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3al0 RCSB], [https://www.ebi.ac.uk/pdbsum/3al0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3al0 ProSAT]</span></td></tr>
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[[3al0]] is a 4 chain structure of [[Aminoacyl tRNA Synthetase]] with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima] and [http://en.wikipedia.org/wiki/Thermotoga_maritima,_synthetic Thermotoga maritima, synthetic]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AL0 OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GATA_THEMA GATA_THEMA] Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/al/3al0_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3al0 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Aminoacyl tRNA Synthetase|Aminoacyl tRNA Synthetase]]
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*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
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*[[Glutamyl-tRNA(Gln) amidotransferase|Glutamyl-tRNA(Gln) amidotransferase]]
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==Reference==
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*[[Transfer RNA (tRNA)|Transfer RNA (tRNA)]]
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<ref group="xtra">PMID:020882017</ref><references group="xtra"/>
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__TOC__
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[[Category: Thermotoga maritima]]
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</StructureSection>
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[[Category: Thermotoga maritima, synthetic]]
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[[Category: Large Structures]]
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[[Category: Ito, T.]]
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[[Category: Synthetic construct]]
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[[Category: Yokoyama, S.]]
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[[Category: Thermotoga maritima MSB8]]
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[[Category: Ligase-rna complex]]
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[[Category: Ito T]]
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[[Category: Protein-rna complex]]
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[[Category: Yokoyama S]]

Current revision

Crystal structure of the glutamine transamidosome from Thermotoga maritima in the glutamylation state.

PDB ID 3al0

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