This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3ay5
From Proteopedia
(Difference between revisions)
| (5 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | {{STRUCTURE_3ay5| PDB=3ay5 | SCENE= }} | ||
| - | ===Crystal structure of HHM (human homologue of murine maternal Id-like molecule)=== | ||
| - | {{ABSTRACT_PUBMED_22453338}} | ||
| - | == | + | ==Crystal structure of HHM (human homologue of murine maternal Id-like molecule)== |
| - | [[ | + | <StructureSection load='3ay5' size='340' side='right'caption='[[3ay5]], [[Resolution|resolution]] 2.50Å' scene=''> |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[3ay5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AY5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AY5 FirstGlance]. <br> |
| - | [[3ay5]] is a 1 chain structure with sequence from [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ay5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ay5 OCA], [https://pdbe.org/3ay5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ay5 RCSB], [https://www.ebi.ac.uk/pdbsum/3ay5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ay5 ProSAT]</span></td></tr> | |
| - | == | + | </table> |
| - | < | + | == Function == |
| + | [https://www.uniprot.org/uniprot/CCDB1_HUMAN CCDB1_HUMAN] May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription.<ref>PMID:10801854</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Ishitani R]] |
| - | [[Category: | + | [[Category: Nureki O]] |
| - | [[Category: | + | [[Category: Seto A]] |
| - | + | ||
Current revision
Crystal structure of HHM (human homologue of murine maternal Id-like molecule)
| |||||||||||
