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3icv

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[[Image:3icv.png|left|200px]]
 
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{{STRUCTURE_3icv| PDB=3icv | SCENE= }}
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==Structural Consequences of a Circular Permutation on Lipase B from Candida Antartica==
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<StructureSection load='3icv' size='340' side='right'caption='[[3icv]], [[Resolution|resolution]] 1.49&Aring;' scene=''>
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===Structural Consequences of a Circular Permutation on Lipase B from Candida Antartica===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3icv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Moesziomyces_antarcticus Moesziomyces antarcticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ICV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ICV FirstGlance]. <br>
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{{ABSTRACT_PUBMED_19683009}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.49&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3icv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3icv OCA], [https://pdbe.org/3icv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3icv RCSB], [https://www.ebi.ac.uk/pdbsum/3icv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3icv ProSAT]</span></td></tr>
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[[3icv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Candida_antarctica Candida antarctica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ICV OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LIPB_PSEA2 LIPB_PSEA2] Hydrolysis of triglycerides. Is very stereospecific both in hydrolysis and in organic synthesis and has a potentially important application in glucolipid synthesis.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ic/3icv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3icv ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Lipase|Lipase]]
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*[[Lipase 3D Structures|Lipase 3D Structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:019683009</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Candida antarctica]]
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[[Category: Moesziomyces antarcticus]]
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[[Category: Triacylglycerol lipase]]
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[[Category: Cheng X]]
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[[Category: Cheng, X.]]
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[[Category: Horton JR]]
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[[Category: Horton, J R.]]
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[[Category: Jia D]]
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[[Category: Jia, D.]]
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[[Category: Lutz S]]
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[[Category: Lutz, S.]]
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[[Category: Qian Z]]
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[[Category: Qian, Z.]]
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[[Category: Circular permutation]]
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[[Category: Cleavage on pair of basic residue]]
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[[Category: Disulfide bond]]
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[[Category: Glycoprotein]]
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[[Category: Hydrolase]]
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[[Category: Lipid degradation]]
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[[Category: Zymogen]]
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Current revision

Structural Consequences of a Circular Permutation on Lipase B from Candida Antartica

PDB ID 3icv

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