This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5us9
From Proteopedia
(Difference between revisions)
| (3 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | + | ||
==Human bocavirus 4== | ==Human bocavirus 4== | ||
| - | < | + | <SX load='5us9' size='340' side='right' viewer='molstar' caption='[[5us9]], [[Resolution|resolution]] 3.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5us9]] is a 60 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5US9 OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5us9]] is a 60 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_bocavirus_4 Human bocavirus 4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5US9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5US9 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5us9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5us9 OCA], [https://pdbe.org/5us9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5us9 RCSB], [https://www.ebi.ac.uk/pdbsum/5us9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5us9 ProSAT]</span></td></tr> |
</table> | </table> | ||
| - | + | == Function == | |
| + | [https://www.uniprot.org/uniprot/CAPSD_HBOC4 CAPSD_HBOC4] Capsid proteins self-assembles to form an icosahedral capsid with a T=1 symmetry, about 26 nm in diameter, and consisting of 60 copies of three size variants of the capsid proteins, VP1, and VP3, which differ by the presence of an N-terminal extension in the minor protein VP1. The capsid has a channel at the 5-fold axis and there are densities extending the 5-fold axis into the interior of the capsid (PubMed:28331084). The capsid encapsulates the genomic ssDNA (Probable). Binding to the host receptors also induces capsid rearrangements leading to surface exposure of VP1 N-terminus, specifically its phospholipase A2-like region. The additional N-terminal region of isoform Minor capsid protein VP1, called VP1u, may serve as a lipolytic enzyme to breach the endosomal membrane during entry into host cell and might contribute to virus transport to the nucleus (By similarity).[UniProtKB:Q9PZT0]<ref>PMID:28331084</ref> <ref>PMID:28331084</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
| - | </ | + | </SX> |
| - | + | ||
| - | + | ||
| - | + | ||
[[Category: Human bocavirus 4]] | [[Category: Human bocavirus 4]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Agbandje-McKenna M]] |
| + | [[Category: Mietzsch M]] | ||
Current revision
Human bocavirus 4
| |||||||||
