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6coz
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | The entry | + | ==Human CLC-1 chloride ion channel, C-terminal cytosolic domain== |
| + | <SX load='6coz' size='340' side='right' viewer='molstar' caption='[[6coz]], [[Resolution|resolution]] 3.36Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6coz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6COZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6COZ FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.36Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6coz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6coz OCA], [https://pdbe.org/6coz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6coz RCSB], [https://www.ebi.ac.uk/pdbsum/6coz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6coz ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/CLCN1_HUMAN CLCN1_HUMAN] Thomsen and Becker disease. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CLCN1_HUMAN CLCN1_HUMAN] Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport.<ref>PMID:12456816</ref> <ref>PMID:22521272</ref> <ref>PMID:26007199</ref> <ref>PMID:26502825</ref> <ref>PMID:26510092</ref> <ref>PMID:7951242</ref> <ref>PMID:8112288</ref> <ref>PMID:9122265</ref> <ref>PMID:9736777</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Ion channels 3D structures|Ion channels 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: Park | + | </SX> |
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: MacKinnon R]] | ||
| + | [[Category: Park E]] | ||
Current revision
Human CLC-1 chloride ion channel, C-terminal cytosolic domain
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