6dnh
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6dnh is ON HOLD Authors: Sun, Y., Zhang, Y., Hamilton, K., Walz, T., Tong, L. Description: Cryo-EM structure of human CPSF-160-WDR33-CPSF-30-PAS RN...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of human CPSF-160-WDR33-CPSF-30-PAS RNA complex at 3.4 A resolution== | |
| - | + | <SX load='6dnh' size='340' side='right' viewer='molstar' caption='[[6dnh]], [[Resolution|resolution]] 3.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6dnh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Macaca_mulatta_polyomavirus_1 Macaca mulatta polyomavirus 1]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=6bll 6bll]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6DNH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6DNH FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.4Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6dnh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6dnh OCA], [https://pdbe.org/6dnh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6dnh RCSB], [https://www.ebi.ac.uk/pdbsum/6dnh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6dnh ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Tong | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/CPSF1_HUMAN CPSF1_HUMAN] Component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction.<ref>PMID:14749727</ref> |
| - | [[Category: | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </SX> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Macaca mulatta polyomavirus 1]] | ||
| + | [[Category: Hamilton K]] | ||
| + | [[Category: Sun Y]] | ||
| + | [[Category: Tong L]] | ||
| + | [[Category: Walz T]] | ||
| + | [[Category: Zhang Y]] | ||
Current revision
Cryo-EM structure of human CPSF-160-WDR33-CPSF-30-PAS RNA complex at 3.4 A resolution
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