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6mrc
From Proteopedia
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==ADP-bound human mitochondrial Hsp60-Hsp10 football complex== | ==ADP-bound human mitochondrial Hsp60-Hsp10 football complex== | ||
| - | <StructureSection load='6mrc' size='340' side='right'caption='[[6mrc]]' scene=''> | + | <StructureSection load='6mrc' size='340' side='right'caption='[[6mrc]], [[Resolution|resolution]] 3.08Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MRC OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[6mrc]] is a 28 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MRC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6MRC FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.08Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6mrc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mrc OCA], [https://pdbe.org/6mrc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6mrc RCSB], [https://www.ebi.ac.uk/pdbsum/6mrc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6mrc ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/CH60_HUMAN CH60_HUMAN] Autosomal dominant spastic paraplegia type 13;Pelizaeus-Merzbacher-like disease due to HSPD1 mutation. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CH60_HUMAN CH60_HUMAN] Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix. | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Heat Shock Protein structures|Heat Shock Protein structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Azem A]] | [[Category: Azem A]] | ||
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[[Category: Malik R]] | [[Category: Malik R]] | ||
[[Category: Nissemblat S]] | [[Category: Nissemblat S]] | ||
| + | [[Category: Patra M]] | ||
[[Category: Ubarretxena-Belandia I]] | [[Category: Ubarretxena-Belandia I]] | ||
Current revision
ADP-bound human mitochondrial Hsp60-Hsp10 football complex
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