Structural highlights
Function
CASTO_LOTJA Ion channel with a moderate preference for potassium over sodium and calcium. Involved in perinuclear calcium spiking but not in cytosolic calcium influx. Closed at negative voltages in presence of magnesium. Required for early signal transduction events leading to endosymbiosis. Acts early in a signal transduction chain leading from the perception of Nod factor to the activation of calcium spiking. Also involved in fungal entry into root epidermal cells during the establishment of the arbuscular mycorrhizal symbiosis.[1] [2]
References
- ↑ Miwa H, Sun J, Oldroyd GE, Downie JA. Analysis of Nod-factor-induced calcium signaling in root hairs of symbiotically defective mutants of Lotus japonicus. Mol Plant Microbe Interact. 2006 Aug;19(8):914-23. doi: 10.1094/MPMI-19-0914. PMID:16903357 doi:http://dx.doi.org/10.1094/MPMI-19-0914
- ↑ Charpentier M, Bredemeier R, Wanner G, Takeda N, Schleiff E, Parniske M. Lotus japonicus CASTOR and POLLUX are ion channels essential for perinuclear calcium spiking in legume root endosymbiosis. Plant Cell. 2008 Dec;20(12):3467-79. doi: 10.1105/tpc.108.063255. Epub 2008 Dec, 23. PMID:19106374 doi:http://dx.doi.org/10.1105/tpc.108.063255
