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1aaz

From Proteopedia

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Current revision (15:22, 13 March 2024) (edit) (undo)
 
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[[Image:1aaz.png|left|200px]]
 
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==THE STRUCTURE OF OXIDIZED BACTERIOPHAGE T4 GLUTAREDOXIN (THIOREDOXIN)==
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The line below this paragraph, containing "STRUCTURE_1aaz", creates the "Structure Box" on the page.
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<StructureSection load='1aaz' size='340' side='right'caption='[[1aaz]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1aaz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AAZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AAZ FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene></td></tr>
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{{STRUCTURE_1aaz| PDB=1aaz | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1aaz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1aaz OCA], [https://pdbe.org/1aaz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1aaz RCSB], [https://www.ebi.ac.uk/pdbsum/1aaz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1aaz ProSAT]</span></td></tr>
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</table>
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===THE STRUCTURE OF OXIDIZED BACTERIOPHAGE T4 GLUTAREDOXIN (THIOREDOXIN)===
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== Function ==
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[https://www.uniprot.org/uniprot/GLRX_BPT4 GLRX_BPT4] Serves as a reducing agent for the phage-induced ribonucleotide reductase, but not for the bacterial ones. This specificity may be the result of sequence differences around the redox-active disulfide bond. The oxidized form accepts electrons from bacterial glutathione and will, in turn, reduce other small disulfides. Can also be reduced by NADPH and by bacterial thioredoxin reductase.<ref>PMID:8440680</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_1453466}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 1453466 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aa/1aaz_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_1453466}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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[[1aaz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AAZ OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1aaz ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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<ref group="xtra">PMID:001453466</ref><ref group="xtra">PMID:009099998</ref><references group="xtra"/>
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<references/>
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[[Category: Enterobacteria phage t4]]
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__TOC__
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[[Category: Eklund, H.]]
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</StructureSection>
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[[Category: Ingelman, M.]]
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[[Category: Escherichia virus T4]]
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[[Category: Joelson, T.]]
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[[Category: Large Structures]]
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[[Category: Nikkola, M.]]
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[[Category: Eklund H]]
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[[Category: Nordlund, P.]]
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[[Category: Ingelman M]]
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[[Category: Petratos, K.]]
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[[Category: Joelson T]]
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[[Category: Soderberg, B O.]]
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[[Category: Nikkola M]]
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[[Category: Sonnerstam, U.]]
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[[Category: Nordlund P]]
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[[Category: Uhlin, T.]]
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[[Category: Petratos K]]
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[[Category: Electron transport]]
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[[Category: Soderberg B-O]]
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[[Category: Sonnerstam U]]
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[[Category: Uhlin T]]

Current revision

THE STRUCTURE OF OXIDIZED BACTERIOPHAGE T4 GLUTAREDOXIN (THIOREDOXIN)

PDB ID 1aaz

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