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1acy

From Proteopedia

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[[Image:1acy.png|left|200px]]
 
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{{STRUCTURE_1acy| PDB=1acy | SCENE= }}
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==CRYSTAL STRUCTURE OF THE PRINCIPAL NEUTRALIZING SITE OF HIV-1==
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<StructureSection load='1acy' size='340' side='right'caption='[[1acy]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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===CRYSTAL STRUCTURE OF THE PRINCIPAL NEUTRALIZING SITE OF HIV-1===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1acy]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/HIV-1_M:B_MN HIV-1 M:B_MN] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ACY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ACY FirstGlance]. <br>
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{{ABSTRACT_PUBMED_7511253}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1acy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1acy OCA], [https://pdbe.org/1acy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1acy RCSB], [https://www.ebi.ac.uk/pdbsum/1acy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1acy ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1acy]] is a 3 chain structure of [[Antibody]] with sequence from [http://en.wikipedia.org/wiki/Hiv-1_m:b_mn Hiv-1 m:b_mn] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ACY OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/IGH1M_MOUSE IGH1M_MOUSE]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ac/1acy_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1acy ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Antibody|Antibody]]
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*[[Antibody 3D structures|Antibody 3D structures]]
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*[[3D structures of non-human antibody|3D structures of non-human antibody]]
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==Reference==
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__TOC__
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<ref group="xtra">PMID:007511253</ref><ref group="xtra">PMID:011599031</ref><references group="xtra"/>
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</StructureSection>
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[[Category: Hiv-1 m:b_mn]]
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[[Category: HIV-1 M:B_MN]]
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Ghiara, J B.]]
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[[Category: Ghiara JB]]
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[[Category: Wilson, I A.]]
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[[Category: Wilson IA]]

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CRYSTAL STRUCTURE OF THE PRINCIPAL NEUTRALIZING SITE OF HIV-1

PDB ID 1acy

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