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1ajs

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[[Image:1ajs.png|left|200px]]
 
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{{STRUCTURE_1ajs| PDB=1ajs | SCENE= }}
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==REFINEMENT AND COMPARISON OF THE CRYSTAL STRUCTURES OF PIG CYTOSOLIC ASPARTATE AMINOTRANSFERASE AND ITS COMPLEX WITH 2-METHYLASPARTATE==
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<StructureSection load='1ajs' size='340' side='right'caption='[[1ajs]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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===REFINEMENT AND COMPARISON OF THE CRYSTAL STRUCTURES OF PIG CYTOSOLIC ASPARTATE AMINOTRANSFERASE AND ITS COMPLEX WITH 2-METHYLASPARTATE===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1ajs]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AJS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AJS FirstGlance]. <br>
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{{ABSTRACT_PUBMED_9211866}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene>, <scene name='pdbligand=PLA:2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-2-METHYL-SUCCINIC+ACID'>PLA</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ajs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ajs OCA], [https://pdbe.org/1ajs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ajs RCSB], [https://www.ebi.ac.uk/pdbsum/1ajs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ajs ProSAT]</span></td></tr>
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[[1ajs]] is a 2 chain structure of [[Aspartate Aminotransferase]] with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AJS OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AATC_PIG AATC_PIG] Plays a key role in amino acid metabolism.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aj/1ajs_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ajs ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Aspartate Aminotransferase|Aspartate Aminotransferase]]
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*[[Aspartate aminotransferase 3D structures|Aspartate aminotransferase 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:009211866</ref><references group="xtra"/>
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[[Category: Large Structures]]
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[[Category: Aspartate transaminase]]
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[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
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[[Category: Arnone, A.]]
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[[Category: Arnone A]]
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[[Category: Hyde, C C.]]
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[[Category: Hyde CC]]
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[[Category: Metzler, C M.]]
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[[Category: Metzler CM]]
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[[Category: Metzler, D E.]]
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[[Category: Metzler DE]]
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[[Category: Rhee, S.]]
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[[Category: Rhee S]]
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[[Category: Rogers, P H.]]
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[[Category: Rogers PH]]
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[[Category: Silva, M M.]]
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[[Category: Silva MM]]
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[[Category: Aminotransferase]]
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[[Category: Cytosolic aspartate aminotransferase]]
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[[Category: In the presence of ligand 2-methylaspartate]]
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[[Category: Pig]]
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Current revision

REFINEMENT AND COMPARISON OF THE CRYSTAL STRUCTURES OF PIG CYTOSOLIC ASPARTATE AMINOTRANSFERASE AND ITS COMPLEX WITH 2-METHYLASPARTATE

PDB ID 1ajs

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