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1ak0

From Proteopedia

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[[Image:1ak0.png|left|200px]]
 
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{{STRUCTURE_1ak0| PDB=1ak0 | SCENE= }}
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==P1 NUCLEASE IN COMPLEX WITH A SUBSTRATE ANALOG==
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<StructureSection load='1ak0' size='340' side='right'caption='[[1ak0]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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===P1 NUCLEASE IN COMPLEX WITH A SUBSTRATE ANALOG===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1ak0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Penicillium_citrinum Penicillium citrinum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AK0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AK0 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_9726413}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADS:ADENOSINE-5-(DITHIO)PHOSPHATE'>ADS</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=THS:THYMIDINE-5-(DITHIO)PHOSPHATE'>THS</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ak0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ak0 OCA], [https://pdbe.org/1ak0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ak0 RCSB], [https://www.ebi.ac.uk/pdbsum/1ak0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ak0 ProSAT]</span></td></tr>
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[[1ak0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Penicillium_citrinum Penicillium citrinum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AK0 OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/NUP1_PENCI NUP1_PENCI] Hydrolyzes only single-stranded DNA and RNA without apparent specificity for bases.
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<ref group="xtra">PMID:009726413</ref><references group="xtra"/>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ak/1ak0_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ak0 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Penicillium citrinum]]
[[Category: Penicillium citrinum]]
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[[Category: Romier, C.]]
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[[Category: Romier C]]
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[[Category: Suck, D.]]
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[[Category: Suck D]]
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[[Category: Endonuclease]]
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[[Category: Glycosylated protein]]
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[[Category: P1 nuclease]]
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[[Category: Reaction mechanism]]
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[[Category: Thiophosphorylated oligonucleotide]]
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Current revision

P1 NUCLEASE IN COMPLEX WITH A SUBSTRATE ANALOG

PDB ID 1ak0

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