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1amn

From Proteopedia

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{{Seed}}
 
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[[Image:1amn.png|left|200px]]
 
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==TRANSITION STATE ANALOG: ACETYLCHOLINESTERASE COMPLEXED WITH M-(N,N,N-TRIMETHYLAMMONIO)TRIFLUOROACETOPHENONE==
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The line below this paragraph, containing "STRUCTURE_1amn", creates the "Structure Box" on the page.
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<StructureSection load='1amn' size='340' side='right'caption='[[1amn]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1amn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Tetronarce_californica Tetronarce californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AMN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AMN FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAF:M-(N,N,N-TRIMETHYLAMMONIO)-2,2,2-TRIFLUORO-1,1-DIHYDROXYETHYLBENZENE'>NAF</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1amn| PDB=1amn | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1amn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1amn OCA], [https://pdbe.org/1amn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1amn RCSB], [https://www.ebi.ac.uk/pdbsum/1amn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1amn ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ACES_TETCF ACES_TETCF] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. May be involved in cell-cell interactions.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/am/1amn_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1amn ConSurf].
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<div style="clear:both"></div>
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===TRANSITION STATE ANALOG: ACETYLCHOLINESTERASE COMPLEXED WITH M-(N,N,N-TRIMETHYLAMMONIO)TRIFLUOROACETOPHENONE===
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==See Also==
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*[[Acetylcholinesterase 3D structures|Acetylcholinesterase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1AMN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AMN OCA].
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[[Category: Large Structures]]
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[[Category: Acetylcholinesterase]]
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[[Category: Tetronarce californica]]
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[[Category: Single protein]]
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[[Category: Harel M]]
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[[Category: Torpedo californica]]
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[[Category: Silman I]]
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[[Category: Harel, M.]]
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[[Category: Sussman JL]]
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[[Category: Silman, I.]]
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[[Category: Sussman, J L.]]
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[[Category: Alternative splicing]]
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[[Category: Glycoprotein]]
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[[Category: Gpi-anchor]]
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[[Category: Hydrolase]]
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[[Category: Membrane]]
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[[Category: Muscle]]
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[[Category: Nerve]]
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[[Category: Neurotransmitter degradation]]
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[[Category: Serine esterase]]
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[[Category: Signal]]
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[[Category: Synapse]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 17:10:14 2008''
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Current revision

TRANSITION STATE ANALOG: ACETYLCHOLINESTERASE COMPLEXED WITH M-(N,N,N-TRIMETHYLAMMONIO)TRIFLUOROACETOPHENONE

PDB ID 1amn

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