1att

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:28, 13 March 2024) (edit) (undo)
 
(11 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1att.png|left|200px]]
 
-
<!--
+
==CRYSTAL STRUCTURE OF CLEAVED BOVINE ANTITHROMBIN III AT 3.2 ANGSTROMS RESOLUTION==
-
The line below this paragraph, containing "STRUCTURE_1att", creates the "Structure Box" on the page.
+
<StructureSection load='1att' size='340' side='right'caption='[[1att]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1att]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ATT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ATT FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1att FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1att OCA], [https://pdbe.org/1att PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1att RCSB], [https://www.ebi.ac.uk/pdbsum/1att PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1att ProSAT]</span></td></tr>
-
{{STRUCTURE_1att| PDB=1att | SCENE= }}
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/ANT3_BOVIN ANT3_BOVIN] Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin, matriptase-3/TMPRSS7, as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin (By similarity).
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/at/1att_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1att ConSurf].
 +
<div style="clear:both"></div>
-
===CRYSTAL STRUCTURE OF CLEAVED BOVINE ANTITHROMBIN III AT 3.2 ANGSTROMS RESOLUTION===
+
==See Also==
-
 
+
*[[Antithrombin 3D structures|Antithrombin 3D structures]]
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_8331659}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 8331659 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_8331659}}
+
-
 
+
-
==About this Structure==
+
-
1ATT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ATT OCA].
+
-
 
+
-
==Reference==
+
-
Crystal structure of cleaved bovine antithrombin III at 3.2 A resolution., Mourey L, Samama JP, Delarue M, Petitou M, Choay J, Moras D, J Mol Biol. 1993 Jul 5;232(1):223-41. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8331659 8331659]
+
[[Category: Bos taurus]]
[[Category: Bos taurus]]
-
[[Category: Single protein]]
+
[[Category: Large Structures]]
-
[[Category: Delarue, M.]]
+
[[Category: Delarue M]]
-
[[Category: Moras, D.]]
+
[[Category: Moras D]]
-
[[Category: Mourey, L.]]
+
[[Category: Mourey L]]
-
[[Category: Samama, J P.]]
+
[[Category: Samama JP]]
-
[[Category: Serine proteinase inhibitor]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 17:34:58 2008''
+

Current revision

CRYSTAL STRUCTURE OF CLEAVED BOVINE ANTITHROMBIN III AT 3.2 ANGSTROMS RESOLUTION

PDB ID 1att

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1att"
Personal tools