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1aw5

From Proteopedia

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{{Seed}}
 
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[[Image:1aw5.png|left|200px]]
 
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==5-AMINOLEVULINATE DEHYDRATASE FROM SACCHAROMYCES CEREVISIAE==
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The line below this paragraph, containing "STRUCTURE_1aw5", creates the "Structure Box" on the page.
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<StructureSection load='1aw5' size='340' side='right'caption='[[1aw5]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1aw5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AW5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1AW5 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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{{STRUCTURE_1aw5| PDB=1aw5 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1aw5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1aw5 OCA], [https://pdbe.org/1aw5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1aw5 RCSB], [https://www.ebi.ac.uk/pdbsum/1aw5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1aw5 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HEM2_YEAST HEM2_YEAST] Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/aw/1aw5_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1aw5 ConSurf].
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<div style="clear:both"></div>
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===5-AMINOLEVULINATE DEHYDRATASE FROM SACCHAROMYCES CEREVISIAE===
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==See Also==
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*[[Porphobilinogen synthase|Porphobilinogen synthase]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_9406553}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 9406553 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9406553}}
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==About this Structure==
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1AW5 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1AW5 OCA].
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==Reference==
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<ref group="xtra">PMID:9406553</ref><references group="xtra"/>
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[[Category: Porphobilinogen synthase]]
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[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Cooper, J B.]]
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[[Category: Cooper JB]]
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[[Category: Erskine, P T.]]
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[[Category: Erskine PT]]
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[[Category: Wood, S P.]]
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[[Category: Wood SP]]
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[[Category: Aldolase]]
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[[Category: Dehydratase]]
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[[Category: Tetrapyrrole biosynthesis]]
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[[Category: Tim-barrel octamer]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 00:07:43 2009''
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Current revision

5-AMINOLEVULINATE DEHYDRATASE FROM SACCHAROMYCES CEREVISIAE

PDB ID 1aw5

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