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1bj3

From Proteopedia

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{{Seed}}
 
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[[Image:1bj3.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF COAGULATION FACTOR IX-BINDING PROTEIN (IX-BP) FROM VENOM OF HABU SNAKE WITH A HETERODIMER OF C-TYPE LECTIN DOMAINS==
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The line below this paragraph, containing "STRUCTURE_1bj3", creates the "Structure Box" on the page.
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<StructureSection load='1bj3' size='340' side='right'caption='[[1bj3]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1bj3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Protobothrops_flavoviridis Protobothrops flavoviridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BJ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BJ3 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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{{STRUCTURE_1bj3| PDB=1bj3 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bj3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bj3 OCA], [https://pdbe.org/1bj3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bj3 RCSB], [https://www.ebi.ac.uk/pdbsum/1bj3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bj3 ProSAT]</span></td></tr>
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</table>
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===CRYSTAL STRUCTURE OF COAGULATION FACTOR IX-BINDING PROTEIN (IX-BP) FROM VENOM OF HABU SNAKE WITH A HETERODIMER OF C-TYPE LECTIN DOMAINS===
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== Function ==
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[https://www.uniprot.org/uniprot/SLA_PROFL SLA_PROFL] Anticoagulant protein which binds to the gamma-carboxyglutamic acid-domain regions of factor IX (F9) (but not factor X) in the presence of calcium with a 1 to 1 stoichiometry.<ref>PMID:12695512</ref> <ref>PMID:8749314</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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The line below this paragraph, {{ABSTRACT_PUBMED_10339409}}, adds the Publication Abstract to the page
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Check<jmol>
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(as it appears on PubMed at http://www.pubmed.gov), where 10339409 is the PubMed ID number.
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bj/1bj3_consurf.spt"</scriptWhenChecked>
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{{ABSTRACT_PUBMED_10339409}}
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==About this Structure==
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</jmolCheckbox>
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1BJ3 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Trimeresurus_flavoviridis Trimeresurus flavoviridis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BJ3 OCA].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bj3 ConSurf].
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<div style="clear:both"></div>
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==Reference==
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== References ==
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Crystal structure of coagulation factor IX-binding protein from habu snake venom at 2.6 A: implication of central loop swapping based on deletion in the linker region., Mizuno H, Fujimoto Z, Koizumi M, Kano H, Atoda H, Morita T, J Mol Biol. 1999 May 28;289(1):103-12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10339409 10339409]
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<references/>
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[[Category: Protein complex]]
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__TOC__
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[[Category: Trimeresurus flavoviridis]]
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</StructureSection>
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[[Category: Atoda, H.]]
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[[Category: Large Structures]]
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[[Category: Fujimoto, Z.]]
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[[Category: Protobothrops flavoviridis]]
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[[Category: Kano, H.]]
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[[Category: Atoda H]]
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[[Category: Koizumi, M.]]
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[[Category: Fujimoto Z]]
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[[Category: Mizuno, H.]]
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[[Category: Kano H]]
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[[Category: Morita, T.]]
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[[Category: Koizumi M]]
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[[Category: C-type lectin superfamily]]
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[[Category: Mizuno H]]
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[[Category: Coagulation factor ix-binding]]
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[[Category: Morita T]]
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[[Category: Habu snake]]
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[[Category: Heterodimer]]
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[[Category: Venom]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 19:14:52 2008''
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Current revision

CRYSTAL STRUCTURE OF COAGULATION FACTOR IX-BINDING PROTEIN (IX-BP) FROM VENOM OF HABU SNAKE WITH A HETERODIMER OF C-TYPE LECTIN DOMAINS

PDB ID 1bj3

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