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1bk8

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[[Image:1bk8.png|left|200px]]
 
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{{STRUCTURE_1bk8| PDB=1bk8 | SCENE= }}
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==DETERMINATION OF THE THREE-DIMENSIONAL SOLUTION STRUCTURE OF AESCULUS HIPPOCASTANUM ANTIMICROBIAL PROTEIN 1 (AH-AMP1) BY 1H NMR, 25 STRUCTURES==
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<StructureSection load='1bk8' size='340' side='right'caption='[[1bk8]]' scene=''>
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===DETERMINATION OF THE THREE-DIMENSIONAL SOLUTION STRUCTURE OF AESCULUS HIPPOCASTANUM ANTIMICROBIAL PROTEIN 1 (AH-AMP1) BY 1H NMR, 25 STRUCTURES===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1bk8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aesculus_hippocastanum Aesculus hippocastanum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BK8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BK8 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_10591099}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bk8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bk8 OCA], [https://pdbe.org/1bk8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bk8 RCSB], [https://www.ebi.ac.uk/pdbsum/1bk8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bk8 ProSAT]</span></td></tr>
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==About this Structure==
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</table>
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[[1bk8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Aesculus_hippocastanum Aesculus hippocastanum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BK8 OCA].
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== Function ==
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[https://www.uniprot.org/uniprot/DEF1_AESHI DEF1_AESHI] Possesses antimicrobial activity sensitive to inorganic cations. Binds specifically to the fungal plasma membrane. Has no inhibitory effect on insect gut alpha-amylase.<ref>PMID:10656585</ref> <ref>PMID:7628617</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bk/1bk8_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bk8 ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
*[[Plant defensin|Plant defensin]]
*[[Plant defensin|Plant defensin]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:010591099</ref><references group="xtra"/>
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__TOC__
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</StructureSection>
[[Category: Aesculus hippocastanum]]
[[Category: Aesculus hippocastanum]]
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[[Category: Borremans, F A.M.]]
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[[Category: Large Structures]]
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[[Category: Fant, F.]]
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[[Category: Borremans FAM]]
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[[Category: Antimicrobial]]
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[[Category: Fant F]]
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[[Category: Cysteine-stabilized alfa/ beta motif]]
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[[Category: Plant defensin]]
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Current revision

DETERMINATION OF THE THREE-DIMENSIONAL SOLUTION STRUCTURE OF AESCULUS HIPPOCASTANUM ANTIMICROBIAL PROTEIN 1 (AH-AMP1) BY 1H NMR, 25 STRUCTURES

PDB ID 1bk8

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